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中华临床医师杂志(电子版) ›› 2017, Vol. 11 ›› Issue (17) : 2200 -2205. doi: 10.3877/cma.j.issn.1674-0785.2017.17.008

所属专题: 经典病例 文献

临床病例分析

继发于蛛网膜下腔出血的男性神经性厌食症一例报道并文献复习
刘彦1, 王艳1, 孙晓芳1, 闫彩凤1, 张真稳1, 童萍2, 邵剑3, 冯尚勇1, 李影1,()   
  1. 1. 225001 扬州,江苏省苏北人民医院内分泌科
    2. 225001 扬州,江苏省苏北人民医院心理科
    3. 225001 扬州,江苏省苏北人民医院营养科
  • 收稿日期:2017-03-16 出版日期:2017-09-01
  • 通信作者: 李影

A case of anorexia nervosa secondary to subarachnoid hemorrhage in a young male patient

Yan Liu1, Yan Wang1, Xiaofang Sun1, Caifeng Yan1, Zhenwen Zhang1, Ping Tong2, Jian Shao3, Shangyong Feng1, Ying Li1,()   

  1. 1. Department of Endocrinology, Subei Hospital, Yangzhou 22500, China
    2. Department of Psychology, Subei Hospital, Yangzhou 22500, China
    3. Department of Nutrition Section, Subei Hospital, Yangzhou 22500, China
  • Received:2017-03-16 Published:2017-09-01
  • Corresponding author: Ying Li
  • About author:
    Corresponding author: Li Ying, Email:
引用本文:

刘彦, 王艳, 孙晓芳, 闫彩凤, 张真稳, 童萍, 邵剑, 冯尚勇, 李影. 继发于蛛网膜下腔出血的男性神经性厌食症一例报道并文献复习[J]. 中华临床医师杂志(电子版), 2017, 11(17): 2200-2205.

Yan Liu, Yan Wang, Xiaofang Sun, Caifeng Yan, Zhenwen Zhang, Ping Tong, Jian Shao, Shangyong Feng, Ying Li. A case of anorexia nervosa secondary to subarachnoid hemorrhage in a young male patient[J]. Chinese Journal of Clinicians(Electronic Edition), 2017, 11(17): 2200-2205.

目的

通过报道一例在蛛网膜下腔出血后出现饮食习惯、体质量、内分泌激素、血液指标明显改变的青年男性患者的临床资料,复习相关文献,总结男性神经性厌食症(AN)的临床表现特点,为临床诊断及治疗提供参考依据。

方法

回顾性分析该患者的临床症状特点、内分泌激素的实验室检查、心理科评估、治疗方法及预后,并结合相关文献复习讨论。

结果

根据临床症状、实验室检验、影像学检查、心理科评估,排除其他可能导致消瘦的原因如结核,肿瘤,消化道病变,临床诊断为AN。予补充复合氨基酸,脂肪乳,饮食行为干预结合心理疏导等,未服用精神疾病药物。定期随访,患者体质量逐渐上升,内分泌激素和血常规结果有所好转。

结论

青年男性AN临床少见,易被误诊。一旦疑似AN,应立即联系心理科进行联合诊治,一旦确诊,病死率高,临床治疗相当困难。重建饮食习惯,心理、行为干预及家庭配合相结合的综合治疗比单一的营养支持治疗更为有效。体质量是提示预后和复发的独立危险因素,故监测体质量变化并调整及时调整策略是救治AN患者的有效措施。

Objective

To report a case of young male patient who had obvious changes in eating habits, weight, endocrine hormones, and hematological parameters after subarachnoid hemorrhage and to review the related literature and summarize the clinical features of anorexia nervosa (AN) in male patients in order to provide the reference for its clinical diagnosis and treatment.

Methods

A retrospective analysis of AN was performed by reviewing the related literature to discuss its clinical characteristics, laboratory examinations, psychological evaluation, treatment, and prognosis in a young male patient.

Results

The diagnosis of AN was made in this patient according to the characteristics of the history, laboratory findings, imaging examinations, and psychological evaluation after excluding other diseases that may cause weight loss, such as tuberculosis, tumor, and digestive tract lesions. The patient was given complex amino acids, fat milk, diet therapy, and psychological counseling, after which his body weight gradually increased and his endocrine hormones and blood test results improved. No mental drugs were administered. During the regular follow-up, the patient′s condition improved.

Conclusion

AN in young males is rare and easily misdiagnosed. If AN is suspected, psychologists should be invited to make a multidisciplinary diagnosis timely. AN has a poor prognosis. Rebuilding diet habit, psychiatric behavior intervention, and family cooperation are more effective than single nutritional support therapy. Body weight is an independent index to indicate the prognosis and recovery of AN. Therefore, monitoring the change of body weight and adjusting therapeutic strategy based on body weight is an effective measure to treat AN patients.

图1 患者全身照,骨性标志突出
表1 血常规及空腹血糖检查结果
表2 性激素及甲状腺激素变化
表3 国内外男性神经性厌食症合并脑外伤或脑病变的病例报道
图3 AN患者治疗前后体质量指数的变化曲线
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