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中华临床医师杂志(电子版) ›› 2018, Vol. 12 ›› Issue (12) : 704 -706. doi: 10.3877/cma.j.issn.1674-0785.2018.12.012

所属专题: 经典病例 文献

病例报告

儿童肾移植术后微小病毒B19感染致难治性贫血2例
马强1,(), 徐虹2, 沈茜2, 饶佳2   
  1. 1. 271000 泰安市妇幼保健院儿内科
    2. 200032 上海,复旦大学附属儿科医院肾脏科
  • 收稿日期:2017-10-19 出版日期:2018-06-15
  • 通信作者: 马强

Refractory anemia caused by human parvovirus B19 infection in pediatric renal transplant recipient: a report of two cases

Qiang Ma1(), Hong Xu2, Qian Shen2   

  • Received:2017-10-19 Published:2018-06-15
  • Corresponding author: Qiang Ma
引用本文:

马强, 徐虹, 沈茜, 饶佳. 儿童肾移植术后微小病毒B19感染致难治性贫血2例[J]. 中华临床医师杂志(电子版), 2018, 12(12): 704-706.

Qiang Ma, Hong Xu, Qian Shen. Refractory anemia caused by human parvovirus B19 infection in pediatric renal transplant recipient: a report of two cases[J]. Chinese Journal of Clinicians(Electronic Edition), 2018, 12(12): 704-706.

图1 病例1患者血红蛋白浓度、微小病毒B19核酸检测值变化图(2013年3月7日所测病毒拷贝为1.5×109拷贝/ml,因与其他数据差别太大,无法在图中体现)
图2 病例1患者静脉免疫球蛋白用量、他克莫司浓度及泼尼松用量变化图
图3 病例2患者血红蛋白浓度、微小病毒B19核酸检测值变化图
图4 病例2患者静脉免疫球蛋白用量、他克莫司浓度及泼尼松用量变化图
1
Beckhoff A, Steffen I, Sandoz P, et al. Relapsing severe anaemia due to primary parvovirus B19 infection after renal transplantation: A case report and review of the literature [J]. Nephrol Dial Transplant, 2007, 22(12): 3660-2663。
2
Kooistra K, Mesman HJ, Waal M, et al. Epidemiology of high-level parvovirus B19 viraemia among Dutch blood donors, 2003-2009 [J]. Vox Sang, 2011, 100(3): 261-266.
3
李帅阳, 沈兵, 刘志宏, 等. 肾移植术后人微小病毒B19感染导致纯红细胞增生障碍性贫血 [J]. 现代生物医学进展, 2012, 12(14): 2698-2702.
4
Macdougall IC, Casadevall N, Locatelli F, et al. Incidence of erythropoietin antibody-mediated pure red cell aplasia: the Prospective Immunogenicity Surveillance Registry (PRIMS) [J]. Nephrol Dial Transplant, 2015, 30(3): 451-460.
5
黄森林, 于立新, 邓文锋, 等. 肾移植术后人类微小病毒B19感染致纯红细胞再生障碍性贫血2例并文献复习 [J]. 器官移植, 2015, 6(4): 250-253.
6
邵惠训. 人类微小病毒B19感染的最新进展 [J]. 医学综述, 2011, 17(20): 3063-3064.
7
Waldman M, Kopp JB. Parvovirus B19 and the kidney [J]. Clin J Am Soc Nephrol, 2007, 2(1): 47-56.
8
Isa A, Kasprowicz V, Norbeck O, et al. Prolonged activation of virus-specific CD8T cells after acute B19 infection [J]. PLoS Med, 2005, 2(12): e343.
9
Leisi R, Di Ommaso C, Kempf C, et al. The receptor-binding domain in the VPlu region of parvovirus B19 [J]. Viruss, 2016, 8(3): 61.
10
Renoult E, Bachelet C, Krier-Coudert MJ, et al. Recurrent anemia in kidney transplant recipients with parvovirus B19 infection [J]. Transplant Proc, 2006, 38(7): 2321-2323.
11
Kumar J, Shaver MJ, Abul-Ezz S. Long-term remission of recurrent parvovirus-B associated anemia in a renal transplant recipient induced by treatment with immunoglobulin and positive seroconversion [J]. Transpl Infect Dis, 2005, 7(1): 30-33.
12
Tsinalis D, Dickenmann M, Brunner F, et al. Acute renal failure in a renal allograft recipient treated with intravenous immunoglobulin [J]. Am J Kidney Dis, 2002, 40(3): 667-670.
13
Metallidis S, Papaioannou M, Bokolas G, et al. Acute renal failure following intravenous immunoglobulin therapy in a HIV-infected patient [J]. Clin Nephrol, 2009, 71(2): 196-197.
14
Kwan TH, Tong MK, Siu YP, et al. Acute renal failure related to intravenous immunoglobulin infusion in an elderly woman [J]. Hong Kong Med, 2005, 11(1): 45-49.
15
Chacko B, John GT, Balakrishnan N, et al. Osmotic nephropathy resulting from maltose-based intravenous immunoglobulin therapy [J]. Ren Fail, 2006, 28(2): 193-195.
16
Heegaard ED, Brown KE. Human parvovirus B19 [J]. Clin Microbiol Rev, 2002, 15(3): 485-505.
17
Mouthon k, Guillevin L, Tellier Z. Intravenous immunoglobulinsinautoimmune-orparvovirusB19-mediatedpurered-cell aplasia [J]. Autoimmun Rev, 2005, 4(3): 264-269.
18
Crabol Y, Terrier B, rozenberg F, et al. Intravenous immunoglobulin therapy for pure red cell aplasia related to human parvovirus b19 infection: a retrospective study of 10 patients and review of the literature [J]. Clin Infect Dis, 2013, 56(7): 968-977.
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