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中华临床医师杂志(电子版) ›› 2019, Vol. 13 ›› Issue (09) : 669 -674. doi: 10.3877/cma.j.issn.1674-0785.2019.09.006

所属专题: 文献

临床研究

MR扩散加权成像脑梗死灶形态特征诊断脉络膜前动脉梗死的价值
周倩茹1, 任家利1, 王元伟2, 胡婷2, 王光胜2,()   
  1. 1. 223600 南京中医药大学沭阳附属医院影像科
    2. 223600 徐州医科大学附属沭阳医院神经内科
  • 收稿日期:2019-03-10 出版日期:2019-05-01
  • 通信作者: 王光胜

Diagnostic value of morphological features detected by diffusion weighted imaging in anterior choroidal artery infarction

Qianru Zhou1, Jiali Ren1, Yuanwei Wang2, Ting Hu2, Guangsheng Wang2,()   

  1. 1. Department of Radiology, Affiliated Shuyang Hospital of Nanjing University of Traditional Chinese Medicine, Shuyang 223600, China
    2. Department of Neurology, Affiliated Shuyang Hospital of Xuzhou Medical University, Shuyang 223600, China
  • Received:2019-03-10 Published:2019-05-01
  • Corresponding author: Guangsheng Wang
  • About author:
    Corresponding author: Wang Guangsheng, Email:
引用本文:

周倩茹, 任家利, 王元伟, 胡婷, 王光胜. MR扩散加权成像脑梗死灶形态特征诊断脉络膜前动脉梗死的价值[J/OL]. 中华临床医师杂志(电子版), 2019, 13(09): 669-674.

Qianru Zhou, Jiali Ren, Yuanwei Wang, Ting Hu, Guangsheng Wang. Diagnostic value of morphological features detected by diffusion weighted imaging in anterior choroidal artery infarction[J/OL]. Chinese Journal of Clinicians(Electronic Edition), 2019, 13(09): 669-674.

目的

探讨脉络膜前动脉(AchA)梗死灶形态特征对脉络膜前动脉梗死的诊断价值。

方法

选择2016年4月至2018年4月于徐州医科大学附属沐阳医院诊断为急性AchA梗死患者100例,记录患者年龄、性别、卒中史、高血压、糖尿病、心房颤动和冠心病情况,应用美国国立卫生研究院卒中量表(NIHSS)评估疾病严重程度及入院NIHSS评分。所有患者均接受头颅MR及扩散加权成像(DWI),并根据梗死灶最大径大小分为小梗死灶(最大径<15 mm),中梗死灶(最大径15~20 mm)及大梗死灶(最大径>20 mm)。

结果

AchA梗死灶直径6.1~29.3 mm,平均(14.6±4.8)mm,小梗死灶55例、中梗死灶31例、大梗死灶14例。索条状与其他形态梗死灶在高血压、糖尿病、心房颤动、冠心病、卒中史方面差异无统计学意义;索条状梗死灶患者出现言语障碍比例高于、最大径大于其他形态梗死灶患者(P=0.006、0.001)。大、中、小梗死灶患者在高血压、糖尿病、心脏病、卒中史等方面比较差异无统计学意义,言语障碍、感觉障碍比例差异有统计学意义(P=0.009、0.047)。

结论

AchA梗死患者梗死灶多表现为索条形,且形态与梗死灶大小有关;梗死灶的形态特征对AchA梗死的诊断具有一定价值。

Objective

To observe the imaging characteristics of acute ischemic stroke (AIS) of the anterior choroidal artery (AchA), and then explore the diagnostic value of morphological features of AchA infarction.

Methods

One hundred consecutively patients with AIS who had an imaging diagnosis of AchA infarction were selected. Data including age, gender, stroke history, hypertension, diabetes, atrial fibrillation (AF), and coronary heart disease were recorded. The severity of illness was evaluated using the National Institute of Health stroke scale (NIHSS) and NIHSS score at admission was recorded. All patients underwent brain MR imaging (MRI) and diffusion weighted imaging after admission. According to the maximum diameter of infarcts, they were divided into small infarcts (maximum diameter <15 mm), medium infarcts (maximum diameter 15-20 mm), and large infarcts (maximum diameter >20 mm).

Results

The diameter of AchA infarct was 6.1-29.3 mm, with an average of (14.6±4.8) mm, including 55 small infarctions, 31 medium infarctions, and 14 large infarctions. No difference was found in terms of hypertension, diabetes, atrial fibrillation, coronary artery disease, or stroke history between cord-like infarcts and infarcts of other shapes. In terms of the proportion of speech disorders and diameter, there were greater in patients with cord-like infarcts were than in patients with infarcts of other shapes (P=0.006, 0.001). There was no significant difference in hypertension, diabetes, heart disease and stroke history among the patients with large, medium and small infarcts, but there was a significant difference in the proportion of speech disorder and sensory disorder (P=0.009, 0.047).

Conclusion

AchA infarcts mostly manifest as long cord-like infarcts on diffusion weighted imaging, and the shape is associated with the size of infarcts. The morphological characteristics of infarcts have diagnostic value for AchA infarction.

图1 患者男性,52岁,高血压史,左内囊后肢及侧脑室旁中部长索条形梗死,MR血管成像阴性 a图DWI示左内囊后肢前后索条状高信号梗死灶,最长径25.6 mm(属大梗死灶);b图DWI示左侧脑室旁中后区域梗死灶,梗死灶紧贴侧脑室;c图MR血管成像示左侧颈内动脉及大脑中动脉无明显狭窄
图2 患者男性,74岁,既往体健,右内囊后肢部小索条形梗死,MR血管成像阴性 a图DWI示右内囊膝部近后肢小索条状高信号梗死灶;b图DWI示右内囊后肢索条状梗死灶,最长径13.4 mm(属小梗死灶);c图MR血管成像示右侧颈内动脉及大脑中动脉无明显狭窄
表1 不同梗死灶形态脉络膜前动脉梗死患者临床特征的比较
表2 不同直径梗死灶脉络膜前动脉梗死患者间临床资料的比较
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