切换至 "中华医学电子期刊资源库"

中华临床医师杂志(电子版) ›› 2023, Vol. 17 ›› Issue (02) : 232 -233. doi: 10.3877/cma.j.issn.1674-0785.2023.02.021

病例报告

一例特别的淋巴结边缘区淋巴瘤
李忠清, 黄春妮, 罗琳, 姚奕斌, 许玉玲, 罗军()   
  1. 530021 南宁,广西医科大学第一附属医院血液内科
  • 收稿日期:2021-12-13 出版日期:2023-02-15
  • 通信作者: 罗军
  • 基金资助:
    国家自然科学基金地区科学基金项目(81660038); 广西壮族自治区卫生和计划生育委员会自筹经费科研课题(Z2016286)

A unique case of nodal marginal zone lymphoma

Zhongqing Li, Chunni Huang, Lin Luo   

  • Received:2021-12-13 Published:2023-02-15
引用本文:

李忠清, 黄春妮, 罗琳, 姚奕斌, 许玉玲, 罗军. 一例特别的淋巴结边缘区淋巴瘤[J]. 中华临床医师杂志(电子版), 2023, 17(02): 232-233.

Zhongqing Li, Chunni Huang, Lin Luo. A unique case of nodal marginal zone lymphoma[J]. Chinese Journal of Clinicians(Electronic Edition), 2023, 17(02): 232-233.

图1 患者骨髓形态学。骨髓增生近极度活跃,异常淋巴细胞占65.5%,该类细胞大小不等,椭圆形、类圆形,可见凹陷、切迹,染色质细致,胞浆量少,染蓝色,周边不整,多呈毛刺状
1
Farhi DC. 临床血液、骨髓细胞形态学-正常与病理特征 [M]. 岳保红, 关方霞, 赵杰, 译. 2版. 西安: 第四军医大学出版社, 2014
2
浦全, 姚永华. 实用血液病骨髓病理学彩色图谱 [M]. 北京: 科学出版社, 2018.
3
李增军, 易树华, 徐卫, 等. B细胞慢性淋巴增殖性疾病诊断与鉴别诊断中国专家共识(2018年版) [J]. 中华血液学杂志, 2018, 39(5): 359-365.
4
Maitre E, Cornet E, Troussard X. Hairy cell leukemia: 2020 update on diagnosis, risk stratification, and treatment [J]. Am J Hematol, 2019, 94(12): 1413-1422.
5
Davies H, Bignell GR, Cox C, et al. Mutations of the BRAF gene in human cancer [J]. Nature. 2002, 417(6892): 949-954.
6
Pardanani A, Tefferi A. BRAF mutations in hairy-cell leukemia [J]. N Engl J Med, 2011, 365(10): 961.
7
Waterfall JJ, Arons E, Walker RL, et al. High prevalence of MAP2K1 mutations in variant and IGHV4-34-expressing hairy-cell leukemias [J]. Nat Genet, 2014, 46(1): 8-10.
8
Jebaraj BM, Kienle D, Bühler A, et al. BRAF mutations in chronic lymphocytic leukemia [J]. Leuk Lymphoma, 2013, 54(6): 1177-1182.
9
Jallades L, Baseggio L, Sujobert P, et al. Exome sequencing identifies recurrent BCOR alterations and the absence of KLF2, TNFAIP3 and MYD88 mutations in splenic diffuse red pulp small B-cell lymphoma [J]. Haematologica, 2017, 102(10): 1758-1766.
10
Pillonel V, Juskevicius D, Ng CKY, et al. High-throughput sequencing of nodal marginal zone lymphomas identifies recurrent BRAF mutations [J]. Leukemia, 2018, 32(11): 2412-2426.
11
Chapman MA, Lawrence MS, Keats JJ, et al. Initial genome sequencing and analysis of multiple myeloma [J]. Nature, 2011, 471(7339): 467-472.
No related articles found!
阅读次数
全文


摘要