切换至 "中华医学电子期刊资源库"

中华临床医师杂志(电子版) ›› 2024, Vol. 18 ›› Issue (01) : 105 -108. doi: 10.3877/cma.j.issn.1674-0785.2024.01.018

病例报告

前庭大腺癌应用脱细胞真皮填充保留外阴手术一例并文献复习
刘强1,(), 宣婉丽1, 康媛2, 李佩2   
  1. 1. 710060 西安,西安医学院第三附属医院妇产科
    2. 710068 西安,陕西省第二人民医院妇产科
  • 收稿日期:2023-10-08 出版日期:2024-01-15
  • 通信作者: 刘强

Bartholin gland carcinoma treated with acellular dermal matrix filling and vulvo-sparing surgery: a case report and literature review

Qiang Liu1,(), Wanli Xuan1, Yuan Kang2, Pei Li2   

  1. 1. Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Xi'an Medical University, Xi’an 710060, China
    2. Department of Obstetrics and Gynecology, The Second People's Hospital of Shaanxi Province, Xi'an 710068, China
  • Received:2023-10-08 Published:2024-01-15
  • Corresponding author: Qiang Liu
引用本文:

刘强, 宣婉丽, 康媛, 李佩. 前庭大腺癌应用脱细胞真皮填充保留外阴手术一例并文献复习[J]. 中华临床医师杂志(电子版), 2024, 18(01): 105-108.

Qiang Liu, Wanli Xuan, Yuan Kang, Pei Li. Bartholin gland carcinoma treated with acellular dermal matrix filling and vulvo-sparing surgery: a case report and literature review[J]. Chinese Journal of Clinicians(Electronic Edition), 2024, 18(01): 105-108.

总结1例前庭大腺癌应用脱细胞真皮(ADM)填充外阴术口及右侧腹股沟淋巴结清扫术野缺损的手术体会。对2022年9月陕西省第二人民医院妇产科收治的1例右侧前庭大腺癌实施保留外阴手术、右侧腹股沟淋巴结清扫及缺损部位应用脱细胞真皮(ADM)填充的围手术期护理进行总结和分析。手术顺利,术后第7 d腹股沟术口周围水肿予以引流,8 d后愈合。会阴部术口脂肪液化,更换敷料10 d后自行愈合,ADM与组织相容度满意,未见局部组织塌陷。术后规范放化疗,至今随访良好。前庭大腺癌是外阴恶性肿瘤中的一种罕见类型,早期制定肿瘤病灶扩大切除、患侧腹股沟淋巴结清扫以保留外阴结构及形态完整,应用ADM填充术野局部组织缺损并结合系统化护理措施,以提高患者术后的生活质量。

To summarize our experience with using acellular dermal matrix (ADM) to fill the defect site of vulva-sparing surgery and right inguinal lymph node dissection in a case of Bartholin gland carcinoma. A case of right Bartholin gland carcinoma admitted to the Department of Obstetrics and Gynecology of the Second People's Hospital of Shaanxi Province in September 2022 was summarized and analyzed for perioperative nursing care, including vulva-sparing surgery, right inguinal lymph node dissection, and defect site filling with ADM. The surgery was successful, and on the 7th day after the surgery, the edema around the inguinal incision was drained, and it healed after 8 days. Perineal fat liquefaction at the surgical site self-healed after 10 days of replacement of dressings. ADM had satisfactory tissue compatibility, and no local tissue collapse was observed. Standardized postoperative radiotherapy and chemotherapy were given, and the patient has good follow-up results so far. Bartholin gland carcinoma is a rare type of malignant tumor of the vulva. Extensive tumor resection and affected inguinal lymph node dissection should be performed in the early stage to preserve the integrity of the structure and morphology of the vulva. ADM can be used to fill the local tissue defect in the surgical field and combined with systematic nursing measures to improve the quality of life of patients after operation.

图1 右侧BGC病灶扩大切除后以ADM填充
图2 右侧腹股沟浅层淋巴结清扫,保留血管
1
Bhalwal AB, Nick AM, Dos Reis R, et al. Carcinoma of the Bartholin Gland: A Review of 33 Cases[J]. Int J Gynecol Cancer, 2016, 26(4): 785-789.
2
Nasu K, Kawano Y, Takai N, et al. Adenoid cystic car-cinoma of Bartholin' s gland. Case report with review of the literature[J]. Gynecol Obstet Invest, 2005, 59(2): 54-58.
3
Nazeran T, Cheng AS, Karnezis AN, et al. Bartholin gland carcinoma: clinicopathologic features, including p16 expression and clinical outcome[J]. Int J Gynecol Pathol, 2019, 38(2): 189-195.
4
Hacker NF, Eifel PJ, van der Velden J. Cancer of the vulva[J]. Int J Gynecol Obstet, 2015, 131(Suppl2): S76-83.
5
Kang YJ, Smith M, Barlow E, et al. Vulvar cancer in high-income countries: increasing burden of disease[J]. Int J Cancer, 2017, 141(11): 2174-2186.
6
Barlow EL, Kang YJ, Hacker NF, et al. Changing trends in vulvar cancer incidence and mortality rates in Australia since 1982[J]. Int J Gynecol Cancer, 2015, 25(9): 1683-1689.
7
Di Donato V, Casorelli A, Bardhi E, et al. Bartholin gland cancer[J]. Crit Rev Oncol ematol, 2017, 117: 1-11.
8
Finan MA, Barre G. Bartholin's gland carcinoma, malignant melanoma and other rare tumours of the vulva[J]. Best Pract Res Clin Obstet Gynaecol, 2003, 17(4): 609-633.
9
Addley S, Sadeghi N, Smyth SL, et al. Bartholin's gland carcinoma-the diagnostic and management challenges of a rare malignancy-a case report and review of current literature[J]. Transl Cancer Res, 2023, 12(1): 201-208.
10
Ouldamer L, Chraibi Z, Arbion F, et al. Bartholin's gland carcinoma: epidemiology and therapeutic management[J]. Surg Oncol, 2013, 22(2): 117-122.
11
Bleier BS. Case of the month[J]. Int Forum Allergy Rhinol, 2017, 7(12): 1119-1120.
12
Billingsley C, Jackson A, Loreen A. 29-year-old with dyspareunia and vulvar mass: An unusual diagnosis of Bartholin's gland carcinoma[J]. Gynecol Oncol Rep, 2018, 16;27: 15-18.
13
Pellizzon ACA. The adenoid cystic carcinoma of the Bartholin's gland: a literature review[J]. Appl Cancer Res, 2018, 38: 6.
14
Helmi Z, Nori W, Ghani Zghair MA, et al. Bartholin gland carcinoma: A case report. J Pak Med Assoc. 2021, 71(Suppl 9)(12): S86-S88.
15
Wainwright DJ. Use of an acellular allograft dermal matrix (AlloDerm) in the management of full-thickness burns[J]. Burns, 1995, 21(4): 243-248.
16
Carvalho-Júnior JDC, Zanata F, Aloise AC, et al. Acellular dermal matrix in skin wound healing in rabbits - histological and histomorphometric analyses[J]. Clinics (Sao Paulo), 2021, 76: e2066.
17
Butler CE, Langstein HN, Kronowitz SJ. Pelvic, abdominal, and chest wall reconstruction with AlloDerm in patients at increased risk for mesh-related complications[J]. Plast Reconstr Surg, 2005, 116(5): 1263-1275; discussion 1276-1277.
18
Tal H. Subgingival acellular dermal matrix allograft for the treatment of gingival recession: a case report[J]. J Periodontol, 1999, 70(9): 1118-1124.
19
Shorr N, Perry JD, Goldberg RA, et al. The safety and applications of acellular human dermal allograft in ophthalmic plastic and reconstructive surgery: a preliminary report[J]. Ophthalmic Plast Reconstr Surg, 2000, 16(3): 223-230.
20
Buinewicz B, Rosen B. Acellular cadaveric dermis (AlloDerm): a new alternative for abdominal hernia repair[J]. Ann Plast Surg, 2004, 52(2): 188-194.
21
An G, Walter RJ, Nagy K. Closure of abdominal wall defects using acellular dermal matrix[J]. J Trauma, 2004, 56(6): 1266-1275.
22
Chaplin JM, Costantino PD, Wolpoe ME, et al. Use of an acellular dermal allograft for dural replacement: an experimental study[J]. Neurosurgery, 1999, 45(2): 320-327.
23
Macadam SA, Lennox PA. Acellular dermal matrices: Use in reconstructive and aesthetic breast surgery[J]. Can J Plast Surg, 2012, 20(2): 75-89.
24
Breuing KH, Colwell AS. Inferolateral AlloDerm hammock for implant coverage in breast reconstruction[J]. Ann Plast Surg, 2007, 59(3): 250-255.
25
Haney NM, Huang MM, Liu JL, et al. Acellular dermal matrix tissues in genitourinary reconstructive surgery: A review of the literature and case discussions[J]. Sex Med Rev, 2021, 9(3): 488-497.
26
Hill DS, Butterfield A. Bartholin's gland squamous cell carcinoma, a rare vulvar neoplasm[J]. Journal of Diagnostic Medical Sonography, 2010, 26: 296-298.
27
Morgan MA, Mikuta JJ. Surgical management of vulvar cancer[J]. Semin Surg Oncol, 1999, 17(3): 168-172.
28
Khan RS, Abbasi HS. A different strategy for management of a case of adenoid cystic carcinoma of Bartholin gland[J]. J Pak Med Assoc, 2020, 70(8): 1445-1447.
29
Verta S, Christmann C, Brambs CE. Adenoid cystic carcinoma of bartholin's gland: A case report with emphasis on surgical management[J]. Am J Case Rep, 2022, 23: e935707.
30
Mihalečko J, Boháč M, Danišovič L', et al. Acellular dermal matrix in plastic and reconstructive surgery[J]. Physiological research, 2022, 71(Suppl1): S51-S57.
31
Dorney KM, Growdon WB, Clemmer JT, et al. Patient, treatment and discharge factors associated with hospital readmission within 30days after surgery for vulvar cancer[J]. Gynecologic Oncology, 2017, 144(1): 136-139.
[1] 廖晓霜, 曾李, 杨波. 脱细胞同种异体真皮联合自体皮修复糖尿病足创面的临床效果[J]. 中华损伤与修复杂志(电子版), 2024, 19(01): 46-50.
[2] 张健, 刘小龙, 查天建, 姚俊杰, 王傑. 富含血小板血浆联合异种脱细胞真皮基质修复糖尿病足缺血性创面的临床效果[J]. 中华损伤与修复杂志(电子版), 2023, 18(06): 503-506.
[3] 李乐平, 肖琨, 张荣华, 商亮, 靖昌庆. 腹腔镜全胃切除术淋巴结清扫范围与策略[J]. 中华普外科手术学杂志(电子版), 2024, 18(02): 127-130.
[4] 杜晓辉, 崔建新. 腹腔镜右半结肠癌D3根治术淋巴结清扫范围与策略[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 5-8.
[5] 燕速, 霍博文, 徐惠宁. 4K荧光腹腔镜扩大右半结肠CME+D3根治术及No.206、No.204组淋巴结清扫术[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 14-14.
[6] 屈洪波, 朱芳, 徐喆, 武楠, 何建怀, 王先明. 经肌间入路行锁骨下淋巴结清扫在局部晚期乳腺癌中的应用[J]. 中华普外科手术学杂志(电子版), 2023, 17(05): 510-513.
[7] 燕速. 腹腔镜低位直肠癌盆腔侧方淋巴结清扫指征与策略[J]. 中华普外科手术学杂志(电子版), 2023, 17(05): 480-484.
[8] 李子禹, 高翔宇. 根治性全胃切除术Roux-en-Y π形吻合[J]. 中华普外科手术学杂志(电子版), 2023, 17(04): 372-372.
[9] 白雪, 陈宏业, 司惠妍, 刘小涵, 张提. 小切口保留乳头的乳房切除(NSM)腋窝淋巴结清扫即刻扩张器置入术[J]. 中华普外科手术学杂志(电子版), 2023, 17(03): 256-256.
[10] 高新. 前列腺癌特异性实时荧光导航靶向盆腔淋巴结清扫 + 前列腺根治术[J]. 中华腔镜泌尿外科杂志(电子版), 2023, 17(04): 426-426.
[11] 周福兴, 贺艳丽, 张潍. 单孔腹腔镜技术在子宫内膜癌全面分期手术中的应用[J]. 中华腔镜外科杂志(电子版), 2024, 17(01): 55-57.
[12] 潘冰, 吕少诚, 赵昕, 李立新, 郎韧, 贺强. 淋巴结清扫数目对远端胆管癌胰十二指肠切除手术疗效的影响[J]. 中华肝脏外科手术学电子杂志, 2023, 12(06): 608-612.
[13] 廖承煜, 江斌华, 黄龙, 王丹凤, 田毅峰, 陈实. 腹腔镜下肝左叶肝内胆管细胞癌根治术优化三步法的应用价值[J]. 中华肝脏外科手术学电子杂志, 2023, 12(04): 395-400.
[14] 于小鹏, 陈晨, 陈家璐, 童焕军, 邱应和, 吴泓, 宋天强, 何宇, 毛先海, 翟文龙, 程张军, 李敬东, 耿智敏, 汤朝晖. 肝内胆管细胞癌淋巴结清扫患者生存获益的术前临床病理特征[J]. 中华肝脏外科手术学电子杂志, 2023, 12(03): 278-283.
[15] 张智春, 周远达, 曾庆昇, 李鹏, 杨红杰, 孙轶. 以CUSUM方法分析腹腔镜层面优先入路直肠癌侧方淋巴结清扫术的学习曲线[J]. 中华结直肠疾病电子杂志, 2023, 12(03): 200-206.
阅读次数
全文


摘要