切换至 "中华医学电子期刊资源库"

中华临床医师杂志(电子版) ›› 2025, Vol. 19 ›› Issue (02) : 161 -164. doi: 10.3877/cma.j.issn.1674-0785.2025.02.011

病例报告

产科抗磷脂综合征合并重度血小板减少一例
高雅茹1, 高雪2, 陈自力1,()   
  1. 1. 300450 天津,天津市第五中心医院妇产科
    2. 300450 天津,中国医学科学院血液病医院(中国医学科学院血液学研究所)移植中心
  • 收稿日期:2025-02-01 出版日期:2025-02-15
  • 通信作者: 陈自力

Obstetric antiphospholipid syndrome complicated with severe thrombocytopenia:a case report

Yaru Gao, Xue Gao, Zili Chen()   

  • Received:2025-02-01 Published:2025-02-15
  • Corresponding author: Zili Chen
引用本文:

高雅茹, 高雪, 陈自力. 产科抗磷脂综合征合并重度血小板减少一例[J/OL]. 中华临床医师杂志(电子版), 2025, 19(02): 161-164.

Yaru Gao, Xue Gao, Zili Chen. Obstetric antiphospholipid syndrome complicated with severe thrombocytopenia:a case report[J/OL]. Chinese Journal of Clinicians(Electronic Edition), 2025, 19(02): 161-164.

图1 孕期血小板计数表
图2 入院后血小板计数表
1
Dabit JY, Valenzuela-Almada MO, Vallejo-Ramos S, et al.Epidemiology of antiphospholipid syndrome in the general population[J]. Curr Rheumatol Rep, 2022, 23(12): 85.
2
Barbhaiya M, Zuily S, Naden R, et al. The 2023 ACR/EULAR antiphospholipid syndrome classification criteria [J]. Arthritis Rheumatol, 2023, 75(10): 1687-1702.
3
Shi Y, Zhao J, Jiang H, et al. Thrombocytopenia in primary antiphospholipid syndrome: association with prognosis and clinical implications [J]. Rheumatology (Oxford), 2022, 62(1): 256-263.
4
代莉, 周容. 产科抗磷脂综合征的流行病学特点及高危因素 [J]. 实用妇产科杂志, 2023, 39(12): 881-884.
5
Kasht R, Borogovac A, George JN. Frequency and severity of pregnancy complications in women with hereditary thrombotic thrombocytopenic purpura [J]. Am J Hematol, 2020, 95(11):E316-E318.
6
Stephanie G, Valentine L, Emmanuelle B, et al. Immune thrombocytopenia and pregnancy: an exposed/non-exposed cohort study [J]. Blood, 2022, 141(1).
7
Yung KC, Xu CW, Zhang ZW, et al. Investigation on glucocorticoid receptors within platelets from adult patients with immune thrombocytopenia [J]. Hematology, 2020, 25(1): 37-42.
8
Lozano ML, Segú-Vergés C, Coma M, et al. Elucidating the mechanism of action of the attributed immunomodulatory role of eltrombopag in primary immune thrombocytopenia: an in silico approach [J]. Int J Mol Sci, 2021, 22(13): 6907.
9
Chen Y, Xu Y, Li H, et al. A novel anti-CD38 monoclonal antibody for treating immune thrombocytopenia [J]. N Engl J Med, 2024, 390(23):2178-2190.
10
Birocchi S, Podda GM, Manzoni M, et al. Thrombopoietin receptor agonists for the treatment of primary immune thrombocytopenia: a meta-analysis and systematic review [J]. Platelets, 2021, 32(2): 216-226.
11
Zhu XL, Feng R, Huang QS, et al. Prednisone plus IVIg compared with prednisone or IVIg for immune thrombocytopenia in pregnancy:a national retrospective cohort study [J]. Ther Adv Hematol, 2022, 13:20406207221095226.
12
Zhou Y, Hu C, Qi W, et al. Anti-β2GPI-domain I antibody is associated with extra-criteria manifestations in a large prospective antiphospholipid syndrome cohort in China [J]. Lupus Sci Med, 2023,10(2): e000924.
13
Chaturvedi S, Braunstein EM, Yuan X, et al. Complement activity and complement regulatory gene mutations are associated with thrombosis in APS and CAPS [J]. Blood, 2020, 135(4): 239-251.
14
中华医学会围产医学分会. 产科抗磷脂综合征诊断与处理专家共识 [J]. 中华围产医学杂志, 2020, 23(8): 517-522.
15
中华医学会妇产科学分会产科学组. 妊娠期及产褥期静脉血栓栓塞症预防和诊治专家共识 [J]. 中华妇产科杂志, 2021, 56(4): 236-243.
16
Zuily S, Cervera R, Foret T, et al. Thrombocytopenia in antiphospholipid syndrome: Is anticoagulation and/or antiaggregation always required? [J]. Autoimmun Rev, 2024, 23(1): 103417.
No related articles found!
阅读次数
全文


摘要


AI


AI小编
你好!我是《中华医学电子期刊资源库》AI小编,有什么可以帮您的吗?