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中华临床医师杂志(电子版) ›› 2025, Vol. 19 ›› Issue (04) : 320 -322. doi: 10.3877/cma.j.issn.1674-0785.2025.04.012

所属专题: 经典病例

病例报告

睾丸混合性生殖细胞肿瘤一例并文献复习
吴一凡, 姜福金, 张先云, 王苏贵, 王以金, 吴自余()   
  1. 223002 江苏淮安,徐州医科大学附属淮安医院泌尿外科
  • 收稿日期:2025-04-19 出版日期:2025-04-15
  • 通信作者: 吴自余

Testicular mixed germ cell tumor: a case report and literature review

Yifan Wu, Fujin Jiang, Xianyun Zhang   

  • Received:2025-04-19 Published:2025-04-15
引用本文:

吴一凡, 姜福金, 张先云, 王苏贵, 王以金, 吴自余. 睾丸混合性生殖细胞肿瘤一例并文献复习[J/OL]. 中华临床医师杂志(电子版), 2025, 19(04): 320-322.

Yifan Wu, Fujin Jiang, Xianyun Zhang. Testicular mixed germ cell tumor: a case report and literature review[J/OL]. Chinese Journal of Clinicians(Electronic Edition), 2025, 19(04): 320-322.

图1 右侧睾丸5.4 cm×3.9 cm,明显增大,内部回声不均匀,见弥漫性囊性暗区,最大约1.2 cm×0.9 cm,右侧附睾显示欠佳
图2 右侧睾丸可见软组织团块,大小约5.5 cm×6.3 cm,密度欠均匀,内见脂肪密度影,可见分隔,增强扫描呈轻度渐进强化
图3 内部信号稍不均,T2WI呈不均匀高信号,内可见多发分隔样结节影,压脂序列及DWI均呈不均匀高信号,增强后呈轻度延迟强化
图4 肿瘤组织形态学(HE×100)。(右侧睾丸)混合性生殖细胞肿瘤(约50%畸胎瘤、30%胚胎性癌、20%卵黄囊瘤)脉管见癌栓,周边生精小管内见原位生殖细胞肿瘤,精索切缘阴性
图5 免疫组化CD30阳性(HE×100)
1
Cheng L, Lyu B, Roth LM. Perspectives on testicular germ cell neoplasms [J]. Hum Pathol, 2017, 59: 10-25.
2
Moch H, Amin MB, Berney DM, et al. The 2022 World Health Organization classification of tumours of the urinary system and male genital organs-part A: renal, penile, and testicular tumours [J]. Eur Urol, 2022, 82(5): 458-468.
3
Laguna MP, Pizzocaro G, Klepp O, et al. EAU guidelines on testicular cancer [J]. Eur Urol, 2001, 40(2): 102-110.
4
Mosharafa AA, Foster RS, Leibovich BC, et al. Histology in mixed germ cell tumors [J]. J Urol, 2004, 171(4): 1471-1473.
5
沈勤, 饶秋, 余波, 等. 免疫组化染色及FISH检测12号染色体短臂捕获对Ⅱ型睾丸生殖细胞肿瘤的诊断意义 [J]. 中华男科学杂志, 2016, 22(8): 692-697.
6
孔祥田, 夏同礼. 现代泌尿病理学 [M]. 北京:人民卫生出版社, 2002: 360-389.
7
Batool AKarimi NWu XN,et al.Testicular germ cell tumor:a comprehensive review[J].Cell Mol Life Sci,2019,76(9):1713-1727.
8
Revels JW, Wang SS, Gangadhar K, et al. Multimodality radiological pictorial review of testicular carcinoma: From initial staging to restaging [J]. Res Rep Urol, 2020, 12: 599-613.
9
Dieckmann KP, Radtke A, Geczi L, et al. Serum levels of microRNA-371a-3p (M371 test) as a new biomarker of testicular germ cell tumors: results of a prospective multicentric study [J]. J Clin Oncol, 2019, 37(16): 1412-1423.
10
贺慧颖, 饶秋, 赵明, 等. 泌尿及男性生殖系统肿瘤病理诊断免疫组化标志物选择专家共识 [J]. 临床与实验病理学杂志, 2018, 34(3): 237-243.
11
崔翼菲, 耿敬姝. 27例睾丸混合性生殖细胞肿瘤临床病理分析 [J]. 现代肿瘤医学, 2021, 29(10): 1735-1739.
12
Patrikidou A, Cazzaniga W, Berney D, et al.European association of urology guidelines on testicular cancer:2023 update [J]. Eur Urol, 2023, 84(3): 289-301.
13
Ehrlich Y, Rosenbaum E, Baniel J. Late relapse of testis cancer [J]. Curr Urol Rep, 2013, 14(5): 518-524.
14
Damjanov I. Testicular germ cell tumors: serological and immunohistochemical diagnosis [J]. Acta Med Acad, 2021, 50(1): 58-70.
15
Cheng L, Lyu B, Roth LM. Perspectives on testicular germ cell neoplasms [J]. Hum Pathol, 2017, 59: 10-25.
16
单祖卷, 王锦锐, 余闫宏. 睾丸混合性生殖细胞肿瘤11例诊治报告 [J]. 现代泌尿外科杂志, 2023, 28(8): 674-678.
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