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中华临床医师杂志(电子版) ›› 2017, Vol. 11 ›› Issue (15) : 2093 -2096. doi: 10.3877/cma.j.issn.1674-0785.2017.15.007

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综述

脑结构和功能网络在血管性轻度认知障碍诊断中的研究进展
张美清1, 韩彦青,1, 李东芳1   
  1. 1. 030001 太原,山西医科大学第二医院神经内科
  • 收稿日期:2017-04-10 出版日期:2017-08-01
  • 通信作者: 韩彦青

Changes of structural and functional brain network in diagnosis of vascular mild cognitive impairment

Meiqing Zhang1, Yanqing Han,1, Dongfang Li1   

  1. 1. Department of Neurology, the Second Hospital of Shanxi Medical University, Taiyuan 030001, China
  • Received:2017-04-10 Published:2017-08-01
  • Corresponding author: Yanqing Han
  • About author:
    Corresponding author: Han Yanqing, Email:
引用本文:

张美清, 韩彦青, 李东芳. 脑结构和功能网络在血管性轻度认知障碍诊断中的研究进展[J/OL]. 中华临床医师杂志(电子版), 2017, 11(15): 2093-2096.

Meiqing Zhang, Yanqing Han, Dongfang Li. Changes of structural and functional brain network in diagnosis of vascular mild cognitive impairment[J/OL]. Chinese Journal of Clinicians(Electronic Edition), 2017, 11(15): 2093-2096.

血管性轻度认知障碍(VaMCI)是血管性认知障碍(VCI)的早期阶段,VCI是指由脑血管病及其危险因素引起的包涵轻度认知功能缺损到痴呆的一大类综合征。已有研究表明VaMCI的病程是可逆的,早期识别及干预VaMCI,阻止其转化为血管性痴呆(VaD),有着重要意义。但目前VaMCI并无统一的诊断标准。随着神经成像技术的研究和应用,大脑结构网络和功能网络的改变,有望为早期诊断VaMCI提供可靠的生物学标志物。本文就VaMCI患者脑结构及功能网络改变新进展进行综述。

Vascular mild cognitive impairment (VaMCI) is the early stage of vascular cognitive impairment (VCI). VCI consists of a large class of complicated syndromes (mild cognitive impairment to dementia) associated with cerebrovascular disease and its risk factors. Previous studies have shown that the course of VaMCI is reversible. Thus, it is of great significance to identify and intervene VaMCI in the early stage and prevent it from being transformed into vascular dementia (VaD). However, there are currently no uniform diagnostic criteria for VaMCI. With the application of neuroimaging technology, the changes of structural and functional brain network are expected to provide reliable biomarkers for the early diagnosis of VaMCI. In this paper, we review the recent progress in the understanding of the changes of structural and functional brain network in patients with VaMCI.

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