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中华临床医师杂志(电子版) ›› 2019, Vol. 13 ›› Issue (09) : 684 -688. doi: 10.3877/cma.j.issn.1674-0785.2019.09.009

所属专题: 文献

综述

神经调节蛋白4在肥胖及代谢性疾病作用的研究进展
程贤鹦1,(), 何银辉2   
  1. 1. 310033 杭州,浙江医院妇产科
    2. 323000 丽水市中心医院,温州医科大学附属第五医院,浙江大学丽水医院内分泌科
  • 收稿日期:2019-03-16 出版日期:2019-05-01
  • 通信作者: 程贤鹦
  • 基金资助:
    浙江省中医药科技计划项目(2018ZB008)

Role of neuregulin 4 in obesity and metabolic disease

Xianying Cheng1,(), Yinhui He2   

  1. 1. Department of Gynecology and Obstetrics, Zhejiang Hospital, Hangzhou 310033, China
    2. Department of Endocrinology, Lishui Central Hospital, the Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Hospital of Zhejiang University, Lishui 323000, China
  • Received:2019-03-16 Published:2019-05-01
  • Corresponding author: Xianying Cheng
  • About author:
    Corresponding author: Cheng Xianying, Email:
引用本文:

程贤鹦, 何银辉. 神经调节蛋白4在肥胖及代谢性疾病作用的研究进展[J]. 中华临床医师杂志(电子版), 2019, 13(09): 684-688.

Xianying Cheng, Yinhui He. Role of neuregulin 4 in obesity and metabolic disease[J]. Chinese Journal of Clinicians(Electronic Edition), 2019, 13(09): 684-688.

脂肪内分泌因子在维持全身能量平衡和糖脂代谢方面具有重要作用。越来越多的证据表明神经调节蛋白4(NRG4)与肥胖及代谢性疾病的发生发展有密切关系,未来通过深入的研究,NRG4有望成为具有治疗肥胖相关多种疾病生物制剂的潜力。

Adipoendocrine factor plays an important role in maintaining systemic energy balance and glycolipid metabolism. Increasing evidence has shown that neuregulin 4 (NRG4) plays an important role in the development of obesity and metabolic disease. Future studies may result in the development of NRG4 as an effective therapeutic biologic for the treatment of obesity-associated disorders.

图1 NRG4作用机制[13]
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