以全身多发严重骨折为首发表现的亚临床库欣综合征一例

doi:10.3877/cma.j.issn.1674-0785.2019.09.015

中华临床医师杂志(电子版) ›› 2019, Vol. 13 ›› Issue (09) : 712 -713. doi: 10.3877/cma.j.issn.1674-0785.2019.09.015

所属专题：经典病例；文献；

病例报告

以全身多发严重骨折为首发表现的亚临床库欣综合征一例

曹永红¹, 史尔兰¹, 叶军¹, 戴武¹^,^†(

)

^1. 230011　安徽医科大学附属合肥医院（合肥市第二人民医院）内分泌科

收稿日期:2019-03-06 出版日期:2019-05-01
通信作者: 戴武
基金资助:
合肥市科技攻关计划（自筹）项目(合科（2017）3号)

A case of subclinical Cushing syndrome with multiple severe fractures of the whole body as first manifestation

Yonghong Cao¹, Erlan Shi¹, Jun Ye¹

Received:2019-03-06 Published:2019-05-01

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引用本文：

曹永红, 史尔兰, 叶军, 戴武. 以全身多发严重骨折为首发表现的亚临床库欣综合征一例[J]. 中华临床医师杂志(电子版), 2019, 13(09): 712-713.

Yonghong Cao, Erlan Shi, Jun Ye. A case of subclinical Cushing syndrome with multiple severe fractures of the whole body as first manifestation[J]. Chinese Journal of Clinicians(Electronic Edition), 2019, 13(09): 712-713.

图2 肾上腺CT示左肾上腺占位性病变

1	Beirwaltes WH, Sturman MF, Ryo U, et al. Imaging functional nodules of the adrenal glands with 131-I-19-iodocholesterol [J]. J Nucl Med, 1974, 15(4): 246-251.
2	李乐乐，窦京涛. 如何从肾上腺意外瘤中甄选出亚临床库欣综合征 [J]. 中国实用内科杂志, 2017, 37(10): 867-870.
3	李乐乐，赵玲，窦京涛, 等. 尿游离皮质醇对肾上腺意外瘤中亚临床库欣综合征的诊断价值 [J]. 中华医学杂志, 2017, 97(46): 3632-3635.
4	Lee SH, Song KH, Kim J, et al. New diagnostic criteria for subclinical hypercortisolism using postsurgical hypocortisolism: the Co-work of Adrenal Research study [J]. Clin Endocrinol, 2017, 86(1): 10-18.
5	Prague JK, May S, Whitelaw BC. Cushing′s syndrome [J]. BMJ, 2013, 27: 346.
6	Minetto M, Reimondo G, Osella G, et al. Bone loss is more severe in primary adrenal than in pituitary-dependent Cushing’s syndrome [J]. Osteoporos Int, 2004, 15(11): 855-861.
7	Morelli V, Eller-Vainicher C, Salcuni AS, et al. Risk of new vertebral fractures in patients with adrenal incidentaloma with and without subclinical hypercortisolism: a multicenter longitudinal study [J]. J Bone Miner Res, 2011, 26(8): 1816-1821.
8	Pierotti S, Gandini L, Lenzi A, et al. Pre-recptiral regulation of steroid hormones in bone cells:insights on glucocorticoid -induced osteoporosis [J]. J Steroid Biochem Mol Biol, 2008, 108(3-5): 292-299.

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