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中华临床医师杂志(电子版) ›› 2019, Vol. 13 ›› Issue (12) : 943 -946. doi: 10.3877/cma.j.issn.1674-0785.2019.12.014

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综述

维生素D对支气管哮喘气道重塑的治疗作用及意义
高蕾1, 王曦1, 王楠1, 周林福2,()   
  1. 1. 210029 南京医科大学第一附属医院呼吸与危重症医学科
    2. 210029 南京医科大学第一附属医院呼吸与危重症医学科;210029 南京医科大学中西医结合研究所
  • 收稿日期:2019-05-12 出版日期:2019-06-15
  • 通信作者: 周林福
  • 基金资助:
    国家重点研发计划(2018YFC1313600); 国家自然科学基金重点国际(地区)合作研究项目(81820108001); 国家自然科学基金项目(81670029、81370133、81170018); 江苏省医学重点人才项目(ZDRCA2016018); 江苏省333高层次人才工程第二层次培养对象(BRA2019078); 江苏省社会发展重点研发专项(BE2015651); 江苏省研究生科研创新计划(KYCX171285)

Effect of vitamin D on airway remodeling in asthma

Lei Gao1, Xi Wang1, Nan Wang1, Linfu Zhou2,()   

  1. 1. Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China
    2. Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China;Institute of Integrative Medicine, Nanjing Medical University, Nanjing 210029, China
  • Received:2019-05-12 Published:2019-06-15
  • Corresponding author: Linfu Zhou
  • About author:
    Corresponding author: Zhou Linfu, Email:
引用本文:

高蕾, 王曦, 王楠, 周林福. 维生素D对支气管哮喘气道重塑的治疗作用及意义[J/OL]. 中华临床医师杂志(电子版), 2019, 13(12): 943-946.

Lei Gao, Xi Wang, Nan Wang, Linfu Zhou. Effect of vitamin D on airway remodeling in asthma[J/OL]. Chinese Journal of Clinicians(Electronic Edition), 2019, 13(12): 943-946.

气道重塑是哮喘病理生理的重要特征,也是哮喘难以根治的重要原因。研究表明维生素D水平与哮喘的发生发展相关,补充维生素D有益于哮喘症状的控制。维生素D有望成为治疗哮喘及重症哮喘的新选择。

Airway remodeling is not only an important pathophysiological feature of asthma, but also an important reason why asthma is difficult to cure. Studies have indicated that the level of vitamin D is related to the development of asthma. Vitamin D supplementation has positive effects in controlling the asthmatic symptoms. Vitamin D is expected to be a new treatment for asthma and severe asthma.

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