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中华临床医师杂志(电子版) ›› 2020, Vol. 14 ›› Issue (04) : 318 -320. doi: 10.3877/cma.j.issn.1674-0785.2020.04.016

所属专题: 经典病例 文献

病例报告

急性部分分化型粒细胞白血病伴C-KIT共突变一例并文献复习
刘壮1, 覃艳红1, 陈秀花1, 徐智芳1, 任方刚1, 张耀方1, 王宏伟1,()   
  1. 1. 030001 太原,山西医科大学第二医院血液病研究所 血液病分子诊疗山西省重点实验室
  • 收稿日期:2019-08-05 出版日期:2020-04-15
  • 通信作者: 王宏伟

C-KIT co-mutation in acute partially differentiated granulocytic leukemia: a case report and literature review

Zhuang Liu1, Yanhong Qin1, Xiuhua Chen1   

  • Received:2019-08-05 Published:2020-04-15
引用本文:

刘壮, 覃艳红, 陈秀花, 徐智芳, 任方刚, 张耀方, 王宏伟. 急性部分分化型粒细胞白血病伴C-KIT共突变一例并文献复习[J]. 中华临床医师杂志(电子版), 2020, 14(04): 318-320.

Zhuang Liu, Yanhong Qin, Xiuhua Chen. C-KIT co-mutation in acute partially differentiated granulocytic leukemia: a case report and literature review[J]. Chinese Journal of Clinicians(Electronic Edition), 2020, 14(04): 318-320.

图1 患者C-KIT基因Sanger测序结果
图2 微滴式数字聚合酶链式反应检测患者C-KIT基因突变负荷 采用双荧光标记,纵轴的1通道显示C-KIT N822K突变,横轴2通道显示C-KIT野生型(无突变),系统自动分析划定界值,显示该样本的C-KIT N822K突变情况
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