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中华临床医师杂志(电子版) ›› 2022, Vol. 16 ›› Issue (08) : 810 -814. doi: 10.3877/cma.j.issn.1674-0785.2022.08.020

综述

干燥综合征的靶向治疗进展
马豆豆1, 宁武1, 王宽婷1,()   
  1. 1. 100144 北京,北京大学首钢医院风湿免疫科
  • 收稿日期:2021-08-27 出版日期:2022-08-15
  • 通信作者: 王宽婷

Progress in targeted therapy of Sjögren's syndrome

Doudou Ma1, Wu Ning1, Kuanting Wang1,()   

  1. 1. Department of Rheumatology and Immunology, Peking University Shougang Hospital, Beijing 100144, China
  • Received:2021-08-27 Published:2022-08-15
  • Corresponding author: Kuanting Wang
引用本文:

马豆豆, 宁武, 王宽婷. 干燥综合征的靶向治疗进展[J/OL]. 中华临床医师杂志(电子版), 2022, 16(08): 810-814.

Doudou Ma, Wu Ning, Kuanting Wang. Progress in targeted therapy of Sjögren's syndrome[J/OL]. Chinese Journal of Clinicians(Electronic Edition), 2022, 16(08): 810-814.

干燥综合征(SS)是一种以外分泌腺受累为主,可累及全身系统的自身免疫性疾病。患者常因口干、眼干、疲劳、疼痛、脏器受累等,严重影响生活质量。近年来,随着人们对干燥综合征发病机制的深入认识,多种靶向药物正在研发中,有望用于治疗此类患者。

Sj?gren's syndrome (SS) is an autoimmune disease which is characterized by lymphocytic infiltration of exocrine glands and can involve many systems in the body. It affects the quality of life of patients seriously and has many manifestations including dryness of mouth and eyes, fatigue, painful, organ involvement, and so on. Thanks to a deeper understanding of SS pathogenesis in recent years, many new targeted drugs are expected to be promising therapeutic agents for SS.

表1 干燥综合征患者中尚无结果的临床试验
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