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中华临床医师杂志(电子版) ›› 2019, Vol. 13 ›› Issue (08) : 620 -623. doi: 10.3877/cma.j.issn.1674-0785.2019.08.012

所属专题: 急危重症 文献

综述

脓毒症相关免疫机制研究进展
田秀丽1, 刘志军1,(), 王春亭2   
  1. 1. 252000 山东聊城,聊城市人民医院呼吸内科
    2. 250014 济南,山东省立医院重症医学科
  • 收稿日期:2019-02-28 出版日期:2019-04-15
  • 通信作者: 刘志军

Sepsis related immune mechanism

Xiuli Tian1, Zhijun Liu1,(), Chunting Wang2   

  1. 1. Department of Respiratory Medicine, Liaocheng People's Hospital, Liaocheng 252000, China
    2. Department of Critical Care Medicine, Shandong Provincial Hospital, Jinan 250014, China
  • Received:2019-02-28 Published:2019-04-15
  • Corresponding author: Zhijun Liu
  • About author:
    Corresponding author: Liu Zhijun, Email:
引用本文:

田秀丽, 刘志军, 王春亭. 脓毒症相关免疫机制研究进展[J/OL]. 中华临床医师杂志(电子版), 2019, 13(08): 620-623.

Xiuli Tian, Zhijun Liu, Chunting Wang. Sepsis related immune mechanism[J/OL]. Chinese Journal of Clinicians(Electronic Edition), 2019, 13(08): 620-623.

随着对脓毒症免疫机制的深入研究,目前普遍认为,脓毒症的宿主免疫反应包括多个后续的或同时发生的进程,既有过度炎症,也有免疫抑制,其主要机制在于机体免疫功能紊乱,包括固有免疫及适应性免疫反应的异常,本文结合近年脓毒症在免疫机制方面的研究,从固有免疫及适应性免疫两方面探讨脓毒症时机体免疫反应的变化。

With the deepening of study on the immune mechanism of sepsis, it is now generally believed that host immune responses to sepsis involve multiple sequential or concurrent processes, including both excessive inflammation and immunosuppression. The main mechanism is immune dysfunction, including abnormalities in innate and adaptive immune responses. Based on the recent study of immune mechanism in sepsis, we explore the changes of the bodys immune response in sepsis from the perspective of innate immunity and adaptive immunity.

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