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中华临床医师杂志(电子版) ›› 2020, Vol. 14 ›› Issue (08) : 604 -607. doi: 10.3877/cma.j.issn.1674-0785.2020.08.004

所属专题: 文献

临床研究

多排螺旋CT在结肠癌壁外血管侵犯评估中的临床应用
陈勇1, 王苏贵1, 张晓雨1,(), 赵海剑1   
  1. 1. 223001 江苏淮安,徐州医科大学附属淮安医院胃肠外科
  • 收稿日期:2020-03-13 出版日期:2020-08-15
  • 通信作者: 张晓雨
  • 基金资助:
    江苏省第十四批"六大人才高峰"高层次人才选拔培养资助计划(WSW-291)

Clinical application of multidetector computed tomography in detection of extramural vascular invasion in patients with colon cancer

Yong Chen1, Sugui Wang1, Xiaoyu Zhang1,(), Haijian Zhao1   

  1. 1. Department of Gastroenterological Surgery, the Affiliated Huai′an Hospital of Xuzhou Medical University, Huai’an 223001, China
  • Received:2020-03-13 Published:2020-08-15
  • Corresponding author: Xiaoyu Zhang
  • About author:
    Corresponding author: Zhang Xiaoyu, Email:
引用本文:

陈勇, 王苏贵, 张晓雨, 赵海剑. 多排螺旋CT在结肠癌壁外血管侵犯评估中的临床应用[J]. 中华临床医师杂志(电子版), 2020, 14(08): 604-607.

Yong Chen, Sugui Wang, Xiaoyu Zhang, Haijian Zhao. Clinical application of multidetector computed tomography in detection of extramural vascular invasion in patients with colon cancer[J]. Chinese Journal of Clinicians(Electronic Edition), 2020, 14(08): 604-607.

目的

探讨多排螺旋CT检查对结肠癌壁外血管侵犯评估的临床应用价值。

方法

采用回顾性描述性研究方法。收集徐州医科大学附属淮安医院胃肠外科2017年3月至2019年10月收治的56例经电子结肠镜活检并经病理确诊为结肠癌的患者的术前多排螺旋CT影像学资料及根治性切除术后的病理资料,以病理结果作为金标准,采用Kappa检验评价多排螺旋CT与病理检查对结肠癌壁外血管侵犯评估的一致性。

结果

多排螺旋CT正确评估51例,假阳性3例,假阴性2例。结果提示多排螺旋CT与病理对结肠癌壁外血管侵犯的评估具有较好的一致性(κ=0.756,P<0.001)。

结论

多排螺旋CT对结肠癌壁外血管侵犯能够提供较好地评估,有助于对结肠癌患者治疗方案的制定及预后情况的评估提供依据。

Objective

To investigate the clinical value of multidetector computed tomography (MDCT) in the detection of extramural vascular invasion in patients with colon cancer.

Methods

A retrospective and descriptive study was conducted on the MDCT imaging and pathological data of 56 patients who had electronic colonoscopy biopsy and histologically proven primary colon cancer at the Affiliated Huai′an Hospital of Xuzhou Medical University between March 2017 and October 2019. Using pathology as the "gold standard", Kappa coefficient was used to measure the consistency between MDCT and pathology for the diagnosis of extramural vascular invasion.

Results

MDCT correctly diagnosed 51 cases of extramural vascular invasion, with 3 false positives and 2 false negatives. There was a good consistency between MDCT and pathology for the diagnosis of extramural vascular invasion (κ=0.756, P<0.001).

Conclusion

Extramural vascular invasion can be mostly detected by MDCT in patients with colon cancer, which is helpful for choosing treatment options and evaluation of the prognosis of patients with colon cancer.

图1 横结肠癌患者血管侵犯阳性病理图 图a为HE染色(×100),可见脉管侵犯;图b示CD34将血管内皮染成棕褐色,内含癌细胞,证实为血管侵犯(免疫组化SP法,×400)
图2 横结肠癌患者多排螺旋CT检查示肿瘤周边血管边缘毛糙失去原有的光滑度(箭头)
表1 多排螺旋CT评估壁外血管侵犯情况与病理结果比较
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