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中华临床医师杂志(电子版) ›› 2017, Vol. 11 ›› Issue (18) : 2245 -2248. doi: 10.3877/cma.j.issn.1674-0785.2017.18.008

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综述

CA199在消化系统疾病中的诊治价值
滕东伶1, 路国涛1, 王丹1, 侯天钰1, 肖炜明1,()   
  1. 1. 225100 扬州大学附属医院消化科
  • 收稿日期:2017-04-06 出版日期:2017-09-15
  • 通信作者: 肖炜明

Diagnostic and therapeutic value of carbohydrate antigen 199 in digestive system diseases

Dongling Teng1, Guotao Lu1, Dan Wang1, Tianyu Hou1, Weiming Xiao1,()   

  1. 1. Department of Gastroenterology, Affiliated Hospital of Yangzhou University, Yangzhou 225100, China
  • Received:2017-04-06 Published:2017-09-15
  • Corresponding author: Weiming Xiao
  • About author:
    Corresponding author: Xiao Weiming, Email:
引用本文:

滕东伶, 路国涛, 王丹, 侯天钰, 肖炜明. CA199在消化系统疾病中的诊治价值[J]. 中华临床医师杂志(电子版), 2017, 11(18): 2245-2248.

Dongling Teng, Guotao Lu, Dan Wang, Tianyu Hou, Weiming Xiao. Diagnostic and therapeutic value of carbohydrate antigen 199 in digestive system diseases[J]. Chinese Journal of Clinicians(Electronic Edition), 2017, 11(18): 2245-2248.

CA199是一种高分子糖蛋白,主要分布在胎儿的胰腺、胆囊、肝脏、肠管等脏器。CA199在健康成人循环血中含量较低,但在消化系恶性肿瘤患者中明显升高,因此被作为一种重要临床检验指标广泛应用于上述疾病诊断或预后评估。此外,近年研究结果显示CA199在一些消化系良性疾病如胆结石、胰腺炎、良性肝病中等亦有升高。本文就CA199在消化系统疾病中的表达及相关临床意义作一总结。

Carbohydrate antigen 199 (CA199) is a high-molecular-weight glycoprotein that is mainly distributed in the fetal pancreas, gallbladder, liver, and intestine. Circulating blood CA199 level is low in healthy adults, but it is significantly higher in patients with malignant tumors of the digestive tract. Therefore, it is widely used as an important clinical indicator in the diagnosis or prognosis evaluation of these diseases. However, recent studies have shown that CA199 also increases in some gastrointestinal benign diseases such as gallstones, pancreatitis, and benign liver diseases. In this paper, we review the expression of CA199 in different digestive system diseases and the related clinical significance.

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