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中华临床医师杂志(电子版) ›› 2021, Vol. 15 ›› Issue (01) : 47 -51. doi: 10.3877/cma.j.issn.1674-0785.2021.01.009

所属专题: 文献

综述

结直肠癌肿瘤标志物的研究进展
王泓懿1,()   
  1. 1. 102206 北京,北京大学国际医院消化内科
  • 收稿日期:2020-08-26 出版日期:2021-01-15
  • 通信作者: 王泓懿

Progress in research of tumor markers in colorectal cancer

Hongyi Wang1,()   

  1. 1. Department of Gastroenterology, Peking University International Hospital, Beijing 102206, China
  • Received:2020-08-26 Published:2021-01-15
  • Corresponding author: Hongyi Wang
引用本文:

王泓懿. 结直肠癌肿瘤标志物的研究进展[J]. 中华临床医师杂志(电子版), 2021, 15(01): 47-51.

Hongyi Wang. Progress in research of tumor markers in colorectal cancer[J]. Chinese Journal of Clinicians(Electronic Edition), 2021, 15(01): 47-51.

结直肠癌是目前最常见消化道恶性肿瘤之一。由于这类疾病早期常无症状,往往诊断较晚,导致该疾病的死亡率一直居高不下。因此,结直肠癌的早发现、早诊断、早治疗显得尤为重要,而目前其诊断主要依赖内镜、影像学检查以及肿瘤标志物等血清学检查。其中,肿瘤标志物在结直肠癌的诊断、预后判断及检测复发等方面具有重大意义。因此,迫切需要发现可用于结直肠癌早期检测的新型血清生物学标志物。本文对近年来与结直肠癌相关的肿瘤标志物研究进展进行综述,从而指导患者的诊疗及预后判断,发现联合多种肿瘤标志物检测有更高的准确性。

Colorectal cancer is one of the most common malignant tumors of the digestive system. Because colorectal cancer is often asymptomatic at early stages and diagnosed late, its mortality rate is high. Therefore, early detection, diagnosis, and treatment of colorectal cancer are particularly important. At present, colorectal cancer diagnosis depends mainly on endoscopy, imaging examination, and serological examination of tumor markers. Among them, tumor markers detection is an extremely significant method in the diagnosis, prognosis judgment, and detection of recurrence. Therefore, there is an urgent need to find new serum biomarkers for early detection of colorectal cancer. In this paper, we review the progress in the research of tumor markers related to colorectal cancer in recent years, with an aim to guide the diagnosis and estimate the prognosis of colorectal cancer patients. We also suggest that the simultaneous detection of multiple tumor markers has higher accuracy.

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