探讨超声引导下经皮肺穿刺活检技术的诊断价值及并发症的相关影响因素，总结提高穿刺的成功率及降低并发症的发生。

回顾性分析2019年7月至2021年7月在中国科学院大学宁波华美医院介入超声治疗中心行超声引导下经皮肺活检106例病例，将穿刺活检结果与病理最终结果作比较，分析超声引导下经皮肺穿刺技术的诊断准确性及并发症的影响因素。

106例病例中，穿刺病理为恶性者84例（79.2％）；穿刺病理为良性者20例（18.9％），另有孤立性纤维瘤1例（0.9%），胸腺瘤1例（0.9%），106例病例中，并发症发生者32例（30.2%），其中出血17例（16.0%），发生气胸者15例（14.2%）。Logistic回归分析显示：性别、病灶位于上中肺、合并肺气肿是出血发生的显著独立危险因素（P＜0.05）；而性别、年龄、穿刺次数、穿刺体位及是否合并肺气肿与气胸的发生差异均无统计学意义（P＞0.05）。

超声引导下经皮肺活检技术是一种安全有效的穿刺活检技术，性别、穿刺体位、有无肺气肿是影响并发症发生的重要因素。

To assess the diagnostic value of ultrasound-guided percutaneous lung biopsy and identify the risk factors for the development of complications, so as to improve the success rate of puncture and reduce the development of complications.

A retrospective analysis was performed on 106 patients who underwent ultrasound-guided percutaneous lung biopsy at the Ultrasound Interventional Therapy Center, University of Chinese Academy of Sciences Ningbo Huamei Hospital from July 2019 to July 2021. By comparing the biopsy results and pathological results, the diagnostic accuracy of ultrasound guided percutaneous lung puncture was assessed, and the risk factors for the development of complications were identified by logistic regression analysis.

Among the 106 cases included, biopsy pathology suggested malignant lesions in 84 cases (79.2%) and benign lesions in 20 (18.9%); there was also one isolated fibroma (0.9%) and one thymoma (0.9%). Among the 106 cases, 32 (30.2%) had complications, including 17 cases (16.0%) with hemorrhage and 15 (14.2%) with pneumothorax. Logistic regression analysis showed that gender, lesion located in the upper middle lung, and emphysema were significant independent risk factors for bleeding (P＜0.05). Gender, age, puncture frequency, puncture position, emphysema, and pneumothorax had no significant impact on the development of complications (P＞0.05).

Ultrasound-guided percutaneous lung biopsy is a safe and effective biopsy technique. Gender, puncture position, and emphysema are important factors affecting the development of complications.