多模态超声在非肿块型乳腺病变中的研究进展

doi:10.3877/cma.j.issn.1674-0785.2024.04.013

乳腺病变可以表现为肿块型和非肿块型，非肿块型乳腺病变病理类型多样且缺乏典型影像学特征，在乳腺癌诊断中的重要性日益凸显。多模态超声技术，包括常规超声、弹性成像和超声造影，为其识别和鉴别提供了有效工具。本文对这些超声技术在识别非肿块型乳腺病变方面的优势与局限，以及与病理学特征之间的相关性进行综述。

关键词: 非肿块型乳腺病变, 多模态超声, 弹性成像, 超声造影

Breast lesions are categorized into two distinct types: mass type and non-mass type. The significance of non-mass-like breast lesions in the diagnosis of breast cancer has heightened due to their diverse pathological spectra and the absence of characteristic imaging features. Multimodal ultrasound approaches, encompassing B-mode ultrasound, elastography, and contrast-enhanced ultrasound, serve as potent tools for the detection and classification of non-mass-like breast lesions. This review examines the efficacy and constraints of these ultrasonic methodologies in identifying non-mass-like breast lesions, as well as their association with pathological characteristics.

Key words: Non-mass-like breast lesions, Multimodal ultrasound imaging, Elastography, Contrast-enhanced ultrasound

表1 多模态超声对非肿块型乳腺病变诊断价值

文献来源	患者例数	敏感度（%）	特异度（%）	准确度（%）	阳性预测值（%）	阴性预测值（%）	AUC（95%CI）
Zhang等^[15]	79	95.0	77.4	87.3	84.4	92.3	0.862
王伟等^[14]	103	78.6	95.7	86.4	95.7	79.0	0.902
李诗语等^[16]	44	95.2	96.2		95.3	96.1	0.976
Guo等^[13]	100	98.0	94.0	96.0	94.3	97.9	0.960

表1 多模态超声对非肿块型乳腺病变诊断价值

文献来源	患者例数	敏感度（%）	特异度（%）	准确度（%）	阳性预测值（%）	阴性预测值（%）	AUC（95%CI）
Zhang等^[15]	79	95.0	77.4	87.3	84.4	92.3	0.862
王伟等^[14]	103	78.6	95.7	86.4	95.7	79.0	0.902
李诗语等^[16]	44	95.2	96.2		95.3	96.1	0.976
Guo等^[13]	100	98.0	94.0	96.0	94.3	97.9	0.960

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Progress and innovations in multimodal ultrasound imaging for non-mass-like breast lesions

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Progress and innovations in multimodal ultrasound imaging for non-mass-like breast lesions