Application and prospect of CT-guided 125I radioactive particle implantation in treatment of unresectable pancreatic cancer

doi:10.3877/cma.j.issn.1674-0785.2018.03.013

Abstract

Abstract:

In recent years, ¹²⁵I radioactive particle implantation has significantly improved the survival rate and quality of life in patients with unresectable pancreatic cancer, because it can effectively control tumor growth, relieve the pain of patients, and prolong the survival time of the patients. The clinical research of CT-guided ¹²⁵I radioactive particle implantation for the treatment of unresectable pancreatic cancer has greatly increased, and the application of 3D printing template-based individualized treatment planning system has become a hot topic, although particle dose selection is still a challenge. In this paper, we review the progress of CT-guided ¹²⁵I radioactive particle implantation in the treatment of unresectable pancreatic cancer, with an aim to promote its future clinical application.

Key words: Pancreatic cancer, ¹²⁵I radioactive particle, Dosimetry

Weixia Wu, Zhigang Zhou, Mingquan Xing. Application and prospect of CT-guided ¹²⁵I radioactive particle implantation in treatment of unresectable pancreatic cancer[J]. Chinese Journal of Clinicians(Electronic Edition), 2018, 12(03): 181-184.

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References 37

[1]	张喆，金成兵，周崑, 等. 无法手术的中晚期胰腺癌HIFU治疗后的生存分析 [J]. 重庆医学, 2017, 16(64): 2190-2192.
[2]	Li X, Ma G, Ma Q, et al. Neurotransmitter substance P mediates pancreatic cancer perineural invasion via NK-1R in cancer cells [J]. Mol Cancer Res, 2013, 11(3): 294-302.
[3]	胡琰琰，于晓玲. 放射性粒子植入技术治疗胰腺癌的临床研究进展 [J]. 解放军医学院学报, 2017, 38(5): 475-477.
[4]	Du YQ, Li ZS, Jin ZD. Endoscope-assisted brachytherapy for pancreatic cancer: From tumor killing to pain relief and drainage [J]. J Interv Gastroenterol, 2011, 1(1): 23-27.
[5]	盖宝东，舒振波，丁大勇, 等. ¹²⁵I放射性粒子治疗胰腺癌 [J]. 中国普外基础与临床杂志, 2007, 14(5): 582-583.
[6]	Peretz T, Nori D, Hilaris B, et al. Treatment of primary unresectable carcinoma of the pancreas with I-125 implantation [J]. Int J Radiat Oncol Biol Phys, 1989, 17(5): 931-935.
[7]	Parashar B, Arora S, Wernicke AG. Radiation therapy for early stage lung cancer [J]. Semin Intervent Radiol, 2013, 30(2): 185-190.
[8]	Yang M, Fang Z, Yan Z, et al. Transarterial chemoembolisa-tion (TACE) combined with endovascular implantation of an iodine-125 seed strand for the treatment of hepatocellular carcinoma with portal vein tumour thrombosis versus TACE a-lone: a two-arm, randomised clinical trial [J]. J Cancer Res Clin Oncol, 2014, 140(2): 211-219.
[9]	张颖，林琦，袁苑, 等. 3D打印个体化模板联合CT引导¹²⁵I粒子植入治疗胸壁转移瘤1例 [J]. 山东大学学报(医学版), 2016, 4(56): 94-96.
[10]	Jiang P, Liu C, Wang J, et al. Computed tomography (CT) -guided interstitial permanent implantation of (125) I seeds for refractory chest wall metastasis or recurrence [J]. Technol Cancer Res Treat, 2015, 14(1) :11-18.
[11]	Ji B, Zhang W, Liu S, et al. Comparison of iodine-125 seed implantation and pancreaticoduodenectomy in the treatment of pancreatic cancer [J]. Int J Med Sci, 2014, 11(9): 893-896.
[12]	Liu B, Zhou T, Geng J, et al. Percutaneous computed tomography-guided iodine-125 seeds implantation for unresectable pancreatic cancer [J]. Indian J Cancer, 2015, 52(Suppl 2): e69-e74.
[13]	Zhongmin W, Yu L, Fenju L, et al. Clinical efficacy of CT-guided iodine-125 seed implantation therapy in patients with advanced pancreatic cancer [J]. Eur Radiol, 2010, 20(7): 1786-1791.
[14]	伦俊杰，赵俊玲，孙建业, 等. CT引导下¹²⁵I放射性粒子植入联合化疗对中晚期胰腺癌的疗效 [J]. 介入放射学杂志, 2015, 24(6): 494-497.
[15]	张杰，周志刚，吕绍娟, 等. CT导向下放射性粒子¹²⁵I联合化学粒子中人氟安治疗胰腺癌 [J]. 医学信息, 2009, 22(12): 1133-1134.
[16]	李帅，周志刚，高剑波, 等. CT引导下组织间植入¹²⁵I粒子联合替吉奥治疗老年胰腺癌疗效分析 [J]. 郑州大学学报(医学版), 2015, 50(2): 270-273.
[17]	Chen Y, Wang XL, Yan ZP, et al. Damage to pig bile duct caused by intraluminal brachytherapy using a (125)I ribbon [J]. Acta Radiol, 2013, 54(3): 272-277.
[18]	Zhu HD, Guo JH, Zhu GY, et al. A novel biliary stent loaded with (125)I seeds in patients with malignant biliary obstruction: Preliminary results versus a conventional biliary stent [J]. J Hepatol, 2012, 56(5): 1104-1111.
[19]	Yang M, Yan Z, Luo J, et al. A pilot study of intraluminal brachytherapy using (125)I seed strand for locally advanced pancreatic ductal adenocarcinoma with obstructive jaundice [J]. Brachytherapy, 2016, 15(6): 859-864.
[20]	Urzua U, Tapta V, Geraldo MP, et al. Nerve growth factor stimulates cellular proliferation of human epithelial ovarian cancer [J]. Horm Metab Res, 2012, 44(9): 656-661.
[21]	Xu JB, Yang XC, Guo JH, et al. Serum nerve growth factor level indicates therapeutic efficacy of ¹²⁵I seed implantation in advanced pancreatic adenocarcinoma [J]. Eur Rev Med Pharmacol Sci, 2015, 19(18): 3385-3390.
[22]	张颖，林琦，韩明勇, 等. 3D打印个体化模板联合CT引导¹²⁵I粒子植入治疗恶性肿瘤质量评价 [J]. 山东大学学报(医学版), 2016, 54(11): 44-50.
[23]	张宏涛，底学敏，于慧敏, 等. 3D打印模板引导¹²⁵I粒子植入术前术后剂量对比 [J]. 中华医学杂志, 2016, 96(9): 712-715.
[24]	姜玉良，王皓，吉喆, 等. CT引导辅助3D打印个体化非共面模板指导¹²⁵I粒子治疗盆腔复发肿瘤剂量学研究 [J]. 中华放射肿瘤学杂志, 2016, 25(9): 959-964.
[25]	Ikushima H. Radiation therapy: state of the art and the future [J]. J Med Invest, 2010, 57(1-2): 1-11.
[26]	申文江. 放射性粒子植入的创新性临床研究 [J]. 山东大学学报(医学版), 2017, 55(2): 1-3.
[27]	Stewart A, Parashar B, Patel M, et al. American brachy-therapy society consensus guidelines for thoracic brachythe-rapy for lung cancer [J]. Brachytherapy, 2016, 15(1): 1-11．
[28]	Kovtun KA, Wolfsberger L, Niedermayr T, et al. Dosi-metric quality and evolution of edema after low -dose-ratebrachytherapy for small prostates: Implications for the use of newer isotopes [J]. Brachytherapy, 2014, 13(2): 152-156.
[29]	Marcu LG, Lawson JM. Technical and dosimetric as-pects of iodine-125 seed reimplantation in suboptimalprostate implants [J]. Br J Radiol, 2013, 86(1026): 20130058.
[30]	Huang MW, Liu SM, Zhang JG. A digital model indi-vidual template and CT-guided ¹²⁵I seed implants for ma-lignant tumors of the head and neck [J]. J Radiat Res, 2012, 53(6): 973-977.
[31]	Keyes M, Morris WJ, Spadinger I, et al. Radiation on-cology and medical physicists quality assurance in british columbia cancer agency provincial prostate brachyther-apy program [J]. Brachytherapy, 2013, 12(4): 343-355.
[32]	Zhang HT, Di XM, Yu HM, et al. Dose comparison betw een pre and post operation of ¹²⁵I seeds implantation guided by 3D print template [J]. Zhonghua Yi Xue Za Zhi, 2016, 96(9): 712-715.
[33]	Wang ZM, Lu J, Zhang LY, et al. Biological effects of low-dose-rate irradiation of pancreatic carcinoma cells in vitro u-sing ¹²⁵I seeds [J]. World J Gastroenterol, 2015, 21(8): 2336-2342.
[34]	Zhang Y, Lin Q, Han MY, et al. The feasibility of 3D print individual template combination with CT guided iodine-125 seed implantation for malig-nancy [J]. J Shandong University (Health Science), 2016, 54(11): 44-50.
[35]	Feng S, Wang L, Xiao Z, et al. ¹²⁵I seed implant brachy-therapy for painful bone metastases after failure of externalbeam radiation therapy [J]. Medicine, 2015, 94(31): e1253.
[36]	Andren-Sandberg A. Pancreatic cancer: chemotherapy and radiotherapy [J]. N Am J Med Sci, 2011, 3(1): 1-12.
[37]	姜玉良. 北京大学第三医院完成首例CT引导联合3D打印模板指导放射性粒子植入治疗腹膜后复发肿瘤 [J]. 北京大学学报(医学版), 2016, 48(1): 182.

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