Advances in understanding relationship between circular RNAs and diseases

doi:10.3877/cma.j.issn.1674-0785.2018.09.010

Abstract

Abstract:

Circular RNAs are noncoding RNAs formed by 5' and 3' back-splicing of precursor RNAs, which are complementary to endogenous RNAs and function as miRNA sponges and modifiers of genetic transcription. CircRNAs are closely related to the occurrence, development, and therapy of many diseases, which makes circRNAs be potential novel molecular markers and targets for molecular targeted therapy.

Key words: Circular RNA, Noncoding RNA, miRNA sponges, Diseases

Pei Zhang, Chunlin Gao, Zhengkun Xia. Advances in understanding relationship between circular RNAs and diseases[J]. Chinese Journal of Clinicians(Electronic Edition), 2018, 12(09): 530-534.

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https://zhlcyszz.cma-cmc.com.cn/EN/Y2018/V12/I09/530

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