Application of prosthesis assisting postoperative brachytherapy for jaw bone neoplasms

doi:10.3877/cma.j.issn.1674-0785.2018.10.006

Abstract

Abstract:

Objective

To assess the application value of prosthesis assisting postoperative brachytherapy for jaw bone neoplasms.

Methods

From May 2012 to September 2017, 31 advanced malignant jaw tumor patients with jaw defects treated at the Stomatology Department of Xuzhou Central Hospital were retrospectively analyzed. All patients were scanned by means of computed tomography. Three-dimensional models were reconstructed using a treatment planning system and the design of prostheses with radioactive seeds was then implemented. Changes of tumor volume and self-evaluation of clinical effects were both conducted to evaluate the clinical effects of prosthesis. Survival analysis was performed by the Kaplan-Meier method.

Results

The follow-up data showed that the overall response rate was 87.1 %. A progression-free survival of 71.2% and an overall survival of 78.3% were achieved at 2 years. All patients reported no pain or discomfort during the treatment, and they were satisfied with the final prostheses of the shape, color, retention, and stability. No obvious adverse effects were observed after prosthesis restoration.

Conclusion

It is effective and feasible to restore jaw defects with prosthesis. In addition, as a carrier with radioactive seeds, it can assist treatment of malignant tumors.

Key words: Jaw bone neoplasms, Prosthesis, Brachytherapy, Treatment plan system

Xing Wang, Qingfei Meng, Cuiling Shao, Yuting Bai, Jian Meng. Application of prosthesis assisting postoperative brachytherapy for jaw bone neoplasms[J]. Chinese Journal of Clinicians(Electronic Edition), 2018, 12(10): 563-566.

/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://zhlcyszz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1674-0785.2018.10.006

https://zhlcyszz.cma-cmc.com.cn/EN/Y2018/V12/I10/563

Figures/Tables 3

References 16

1	Bidra AS, Jacob RF, Taylor TD. Classification of maxillectomy defects: a systematic review and criteria necessary for a universal description [J]. J Prosthet Dent, 2012, 107(4):261-270.
2	王兴，孟箭，顾倩平, 等. PET-CT在晚期上颌骨恶性肿瘤放射性粒子植入治疗中的应用价值研究 [J/CD]. 中华介入放射学电子杂志, 2016, 4(3):142-145.
3	王兴，孟箭，辜健敏. ¹²⁵I放射性粒子植入治疗腭部癌肉瘤一例 [J]. 中华口腔医学杂志, 2017, 52(12):756-757.
4	Flores-Ruiz R, Castellanos-Cosano L, Serrera-Figallo MA, et al. Evolution of oral cancer treatment in an andalusian population sample: Rehabilitation with prosthetic obturation and removable partial prosthesis [J]. J Clin Exp Dent, 2017, 9(8):e1008-e1014.
5	孟庆飞，孟箭. 赝复体式放射性粒子布源器的设计制作与临床初步应用 [J/CD]. 中华临床医师杂志(电子版), 2012, 6(18):5753-5754.
6	黄明伟，张杰，宋铁砾, 等. 义齿基托布源器治疗颌周恶性肿瘤的初步应用 [J]. 实用口腔医学杂志, 2008, 24(2):244-247.
7	佟岱，黄明伟，张建国, 等. 计算机辅助设计与快速成形技术制作上颌放射性粒子布源器的临床应用 [J]. 北京大学学报(医学版), 2010, 42(1):63-66.
8	王俊杰，柴树德，郑广钧, 等. 3D打印模板辅助CT引导放射性125I粒子植入治疗肿瘤专家共识 [J]. 中华放射医学与防护杂志, 2017, 37(3):161-170
9	赵铱民. 口腔修复学[M]. 7版. 北京: 人民卫生出版社, 2013: 399-423.
10	Gomez-Roca C, Koscielny S, Ribrag V, et al. Tumour growth rates and RECIST criteria in early drug development [J]. Eur J Cancer, 2011, 47(17):2512-2516.
11	Denis F, Garaud P, Bardet E, et al. Late toxicity results of the GORTEC 94-01 randomized trial comparing radiotherapy with concomitant radiochemotherapy for advanced-stage oropharynx carcinoma: comparison of LENT/SOMA, RTOG/EORTC, and NCI-CTC scoring systems [J]. Int J Radiat Oncol Biol Phys, 2003, 55(1):93-98.
12	顾晓宇，陈晓波，焦婷, 等. 三维打印数字化阴模辅助制作口腔颌面缺损赝复体的临床应用 [J]. 中华口腔医学杂志, 2017, 52(6):336-341.
13	谭京，王兵，黄明伟, 等. 腭部恶性肿瘤近距离放疗中义齿基托布源器的设计与制作 [J]. 北京大学学报(医学版), 2011, 43(1):145-147.
14	Liu A, Botkin A, Murray C, et al. Treatment for Lentigo Maligna of the Head and Neck: Survey of Practices in Ontario, Canada [J]. Dermatol Surg, 2018, 44(7):918-923.
15	Osborn VW, Givi B, Rineer J, et al. Patterns of care and outcomes of adjuvant therapy for high-risk head and neckcancer after surgery [J]. Head Neck, 2018, 40(6):1254-1262.
16	白阳，王燕一，张蕾, 等. 基托材料对¹²⁵I粒子屏蔽效果的初步研究 [J]. 中华口腔医学杂志, 2011, 46(8):502-504.

[1]	Peijie Li, Yongjie Qiao, Haoqiang Zhang, Jiankang Zeng, Fei Tan, Jiahuan Li, Jing Wang, Shenghu Zhou. Progress in diagnosis and treatment of periprosthetic infection with negative bacterial culture [J]. Chinese Journal of Joint Surgery(Electronic Edition), 2023, 17(06): 827-833.
[2]	Wen Lin, Yuxuan Wang, Jiayue Xu, Jinqun Wang, Ruina Wang, Dongyuan He, Pei Fan. Research progress of artificial joint replacement registry [J]. Chinese Journal of Joint Surgery(Electronic Edition), 2023, 17(06): 834-841.
[3]	Guiguan Wang, Jie Xu. Research progress in kinematic alignment in total knee arthroplasty [J]. Chinese Journal of Joint Surgery(Electronic Edition), 2023, 17(05): 726-731.
[4]	Hongyi Li, Lang Yang, Guohong Wen, Hong Guan, Jiangying Ru, Xiangjiang Wang. Correlations in sagittal position of femoral componenet of knee arthroplasty and postoperative patellofemoral pain and joint function [J]. Chinese Journal of Joint Surgery(Electronic Edition), 2023, 17(04): 479-484.
[5]	Ying Pi, Gao Wang, Qiang Zhang, Zhirong Huang. Factors analysis on revision surgery after total hip replacement in young patients [J]. Chinese Journal of Joint Surgery(Electronic Edition), 2023, 17(03): 430-434.
[6]	Jun Tan, Lijuan Zhan, Lingxiao Wu, Kehan Cai, Xu Jiang, Tao Chen, Jianzhong Xu. Implantation of antibiotic-loaded calcium sulfate in partial one-stage revision for chronic periprosthetic hip infection [J]. Chinese Journal of Joint Surgery(Electronic Edition), 2023, 17(03): 318-325.
[7]	Lin Tang, Yingbin Wu, Enhao Pan, Weijie Lu. Advances of acetabular component placement in total hip replacement for developmental dysplasia of hip [J]. Chinese Journal of Joint Surgery(Electronic Edition), 2023, 17(01): 65-70.
[8]	Zhijia Wen, Haobo Zhong, Shaowei Zheng, Xu Li, Yin Wang, Guowei Zeng, Shengjie Wang, Chunhan Sun. Research progress of periprosthesis fungal infection after artificial joint replacement [J]. Chinese Journal of Joint Surgery(Electronic Edition), 2023, 17(01): 60-64.
[9]	Junshuai Lu, Liceng Gao, Yiqun Wang, Xiaobin Xu, Wenqian Ma, Wei Zhu. Application value of movable Oxford unicondylar knee replacement in the treatment of spontaneous osteonecrosis of the knee [J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2023, 18(01): 39-46.
[10]	Hanzhi Zhang, Mengting Ding, Wenjun She, Ting Jiao. Digital fabrication of an immediate obturator prosthesis to reconstruct a maxillectomy defect secondary to the chemotherapy/immunosuppression of myelodysplastic syndromes [J]. Chinese Journal of Stomatological Research(Electronic Edition), 2023, 17(04): 253-259.
[11]	Dongyi Wang, Yun Dai, Xinping Yin, Jiali Meng, Guofeng Wu. Development of a retention force measuring system for removable partial denture clasps and preliminary evaluation of its effects [J]. Chinese Journal of Stomatological Research(Electronic Edition), 2023, 17(03): 197-202.
[12]	Wei Zhang, Yang Li, Peizhong Shang, Dandan Shang, Wei Zhang. Adult cryptorchidism extracted by minilaparoscopy during TAPP for indirect inguinal hernia：a case report [J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2023, 17(05): 586-587.
[13]	Junyu Chen, Yu Cui. Clinical analysis of TAPP in the treatment of incarcerated inguinal hernia [J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2023, 17(05): 546-549.
[14]	Yongguo Fan, Yonggang Lyu, Xiaomin Yang, Huxia Wang, Nan Chen, Sai He, Yanni Hou, Jing Zhao, Jingyuan Zhang, Pihua Han. Analysis of outcomes and complications reported by patients undergoing breast reconstruction with different protocols [J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2023, 17(03): 262-266.
[15]	Jiahui Zhao, Zhu Hou, Yong Luo, Mingchuan Li, Tao Peng, Yongxing Wang, Yongguang Jiang. Clinical analysis of urinary complications of brachytherapy in patients of prostate cancer [J]. Chinese Journal of Endourology(Electronic Edition), 2022, 16(05): 400-403.

Please choose a citation manager

Content to export