To verify the efficacy of Caprini and Padua risk assessment models in screening of venous thromboembolism in patients in the department of internal medicine.

A single center retrospective study was performed in the inpatients at the Affiliated Hospital of Qingdao University from August 2017 to December. The Padua and Caprini risk scores were record retrospectively for each patient. Meanwhile, logistic bivariate regression analysis was performed to assess the predictive ability of combined Caprini and Padua risk assessment models for diagnosis of VTE. The operating characteristic curves (ROC) were plotted to calculate the area under the curve and pairwise comparisons were then performed. The cutoff point was chosen based on the Youden index.

The area under the ROC curve of the combination model was significantly higher than that of Caprini or Padua model alone (0.927±0.009 vs 0.739±0.020, Z=10.659, P<0.001; 0.927±0.009 vs 0.817±0.017, Z=8.952, P<0.001).The sensitivity and specificity of the combination model were also higher than those of Caprini or Padua model alone (83.7% vs 79.1% vs 72.1%; 87.9% vs 66.7% vs 82.7%).

The combination of Caprini and Padua risk assessment models can improve the accuracy of screening for VTE in patients in the department of internal medicine.