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Chinese Journal of Clinicians(Electronic Edition) ›› 2021, Vol. 15 ›› Issue (02): 118-122. doi: 10.3877/cma.j.issn.1674-0785.2021.02.007

Special Issue:

• Review • Previous Articles     Next Articles

Fertility preservation in young breast cancer patients

Yuge Bai1, Ling Xu1,(), Yinhua Liu1, Xuening Duan1, Jingming Ye1, Qian Liu1, Yuanjia Cheng1, Ling. Xin1   

  1. 1. Breast Disease Center, Peking University First Hospital, Beijing 100034, China
  • Received:2020-09-03 Online:2021-02-15 Published:2021-06-04
  • Contact: Ling Xu

Abstract:

China's cancer burden is increasing year by year, and breast cancer has the highest incidence among all female malignancies in Chinese women. New cases in China account for 12.2% of all newly diagnosed breast cancer cases worldwide, and deaths account for 9.6% of global breast cancer deaths. Since the National People's Congress Standing Committee voted to pass the amendments to the Population and Family Planning Law on December 27, 2015, the universal two-child policy has made more and more families have childbearing needs. In order to better balance the contradictory problem of the survival and fertility of young breast cancer patients, this article reviews the relevant research at home and abroad. Those studies unanimously observed that women with a history of breast cancer are safe in pregnancy. No reduction in overall survival was observed compared with the non-pregnant group. At the same time, it is safe and feasible to apply fertility protection measures, especially the application of gonadotropin-releasing hormone agonists, to reduce the early risk of menopause and improve fertility prospects. Therefore, clinicians should correctly provide help for breast cancer survivors who have fertility requirements and provide as many opportunities as possible for future pregnancy.

Key words: Breast cancer in young woman, Ovarian function, Gonadotropin-releasing hormone agonist

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