Progress in research of exosomal microRNAs in chronic obstructive pulmonary disease

doi:10.3877/cma.j.issn.1674-0785.2021.03.010

Abstract

Abstract:

Exosomes are pleomorphic vesicle-like bodies secreted by a variety of cells, with a diameter of 30-100 nm, and are widely distributed in various body fluids. Exosomes can influence the biological function of target cells by transferring membrane receptors, proteins, mRNA, microRNAs (miRNAs), and other bioactive molecules, which is a new way of intercellular interaction. Exosomal miRNAs play a key role in the occurrence and development of chronic obstructive pulmonary disease. This article aims to review the cuurent research status of exosomal miRNAs in chronic obstructive pulmonary disease and their potential application value as clinical biomarkers.

Key words: Exosomes, MicroRNAs, Chronic obstructive pulmonary disease

Ruiying Wang, Jianying Xu. Progress in research of exosomal microRNAs in chronic obstructive pulmonary disease[J]. Chinese Journal of Clinicians(Electronic Edition), 2021, 15(03): 205-208.

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