Prognosis of epileptic seizures after cranioplasty

doi:10.3877/cma.j.issn.1674-0785.2021.05.008

Abstract

Abstract:

Objective

To evaluate the prognosis of epileptic seizures after cranioplasty and explore the related factors.

Methods

71 patients with epileptic seizures after cranioplasty at Dezhou People's Hospital from January 2010 to December 2018 were analyzed retrospectively.

Results

63 patients were finally included, including 18 females and 45 males. They ranged in age from 20 to 68 years, with a mean age of (44.10±12.66) years. The median follow-up time was 51.63 months, ranging from 12 to 106 months. Adverse drug reactions occurred in 5 patients after taking antiepileptic drugs. 7 patients with postoperative epileptic seizures died. The favorable prognosis rate of seizures following cranioplasty was 39.7% (25/63). Among them, the favorable prognosis rate of new-onset seizures was 52.4% (22/42), and that of recurrent seizures was 14.3% (3/21), the difference between them was statistically significant (P＜0.05).

Conclusion

In terms of epilepsy symptom control, compared with patients with recurrent seizures after cranioplasty, patients with new-onset seizures have a better prognosis.

Key words: Cranioplasty, Epileptic seizure, Complication, Prognosis

Jun Zhou, Xingyuan Shi, Qingling Zhang, Xianghui Liu, Yunlin Guo, Zhiying Zhang, Jian Zhang. Prognosis of epileptic seizures after cranioplasty[J]. Chinese Journal of Clinicians(Electronic Edition), 2021, 15(05): 356-359.

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URL: https://zhlcyszz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1674-0785.2021.05.008

https://zhlcyszz.cma-cmc.com.cn/EN/Y2021/V15/I05/356

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References 18

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项目	预后良好	预后不良	χ²值	P值
发作时间			1.619	0.102
术后3 d内癫痫发作	9（56.3）	7（43.7）
术后3 d后癫痫发作	16（34.0）	31（66.0）
发作情况			6.971	0.003
术后复发癫痫发作	3（14.3）	18（85.7）
术后新发癫痫发作	22（52.4）	20（47.6）

项目	预后良好	预后不良	χ²值	P值
发作时间			1.619	0.102
术后3 d内癫痫发作	9（56.3）	7（43.7）
术后3 d后癫痫发作	16（34.0）	31（66.0）
发作情况			6.971	0.003
术后复发癫痫发作	3（14.3）	18（85.7）
术后新发癫痫发作	22（52.4）	20（47.6）

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