To investigate the effect of noninvasive ventilation with endoscopic mask and laryngeal mask in disease diagnosis and treatment by indolent fiberoptic bronchoscopy.

One hundred patients scheduled for indolent fiberoptic bronchoscopy between October 2020 and May 2021 at our hospital were randomly divided into two groups: Mask group (group M), laryngeal mask group (group L), with 50 patients in each group. Patients in group M were ventilated with endoscopic mask, and patients in group L were ventilated with laryngeal mask. Patients in both groups received propofol combined with intravenous anesthesia. The anesthesia time and operation time were recorded. Systolic blood pressure (SBP), heart rate (HR), SpO₂, and respiratory rate (RR) were recorded upon entering the operating room (t₀), 2 min after anesthesia induction (t₁), 2 min after the bronchoscope enters the trachea (t₂), and after exiting the tracheoscope (t₃). The patient's satisfaction with anesthesia and the doctor's satisfaction were assessed and recorded. The number of patients with hypoxemia (SpO₂＜90%), and the adverse effects including body movement, cough, laryngeal spasm, and sore throat after examination were also recorded.

Anesthesia time and operation time did not differ significantly between the two groups (P＞0.05). SBP, HR, SpO₂, and RR did not differ between the two groups at each time point (P＞0.05). Compared with group M, the patient's satisfaction with anesthesia and doctor's satisfaction were significantly higher in group L (P＜0.05). The number of patients with hypoxemia in group L was significantly lower than that in group M (P＜0.05). Compared with group L, the incidence of body movement and cough was significantly higher in group M (P＜0.05), though the incidence of laryngeal spasm and sore throat did not differ significantly between the two groups (P＞0.05). Among patients with normal or mild to moderate preoperative lung dysfunction, there was no statistical difference in the incidence of hypoxemia between the two groups (P＞0.05). Compared with group L, the incidence of severe hypoxemia in group M was significantly higher for patients with severe and extremely severe preoperative lung function impairment (P＜0.05).

In patients with normal lung function or mild to moderate lung dysfunction, both endoscopic mask and laryngeal mask combined with non-invasive ventilator assisted ventilation can achieve good ventilation effects, but considering the proportion of consumables, endoscopic mask is preferred. Laryngeal mask ventilation is recommended for patients with severe and extremely severe lung function impairment because of its better ventilation effect, safety, and effectiveness.