To construct a cooperative network for reproductive preservation of gonadal tissue from cancer patients by using informatics technologies, so as to provide quality and safety guarantee for the preservation and application of gonadal tissue from cancer patients.

To meet the changing demand of the business process, the system was built in an iterative and step-by-step manner. A platform framework was designed to develop a collaborative network system of reproductive preservation for cancer patients according to the application requirements of business process and database, information exchange and sharing, data security protection, subsystem function, and data management and analysis.

Polygonal software architecture was used to meet the business requirements of different users. Representational state transition (RESTful) method was employed for data exchange to reduce software description complexity. Hypertext secure transfer protocol (HTTPS) was used for data transmission to ensure the security of data transmission. The system had standardized 97 key fields, including 46 text fields and 51 digital fields. The information content included patients' basic information, physical examination, clinical diagnosis, gonad tissue collection and storage, transplantation and post-transplantation follow-up, and other life-cycle information. By using this system, a closed-loop management of the gondal samples and related information from cancer patients who need fertility protection was achieved.

As one of the bases for the reproductive preservation of cancer patients, this network provides an effective tool for the management of cancer patients' gonad tissues bio-banking procedure, such as sample storage procedure, patient follow-up after transplantation, and environment monitoring and recording. It provides a system to ensure the quality and safety for long-term tissue storage.