Progress in application of heparin-binding protein in sepsis

doi:10.3877/cma.j.issn.1674-0785.2023.04.021

Abstract

Abstract:

Heparin-binding protein (HBP) is a kind of granule protein produced by neutrophils in response to external stimuli. It plays a crucial role in increasing vascular permeability, chemotaxis, and regulating inflammatory response In recent years, studies have found that HBP can be used as an early predictor of sepsis. In addition, it has been confirmed that HBP can be used to evaluate the disease severity and prognosis in sepsis patients. This review focuses on the clinical value of HBP in sepsis.

Key words: Heparin-binding protein, Sepsis, Biomarker

Xing Cai, Ruiqiang Zheng. Progress in application of heparin-binding protein in sepsis[J]. Chinese Journal of Clinicians(Electronic Edition), 2023, 17(04): 487-490.

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