The veins and the lymphatic system are anatomically and functionally interdependent. When the venous and lymphatic systems are abnormal in structure or function, different organ or tissue lesions can occur. Venolymphatic insufficiency patients are distributed in multiple clinical departments, which makes standardized treatment quite difficult. In international guidelines and consensus, venolymphatic insufficiency related diseases and their diagnosis and treatment are gradually updated. In China, there is no clear consensus on the definition of venolymphatic insufficiency and the diagnosis and treatment of its related diseases. In order to deepen the understanding of venolymphatic insufficiency, our expert team standardizes its definition, and elaborates its etiology, pathophysiological changes, clinical manifestations, diseases involved, prevention, and treatment, by combining the existing international and domestic literature and multidisciplinary expert opinions. The consensus developed can provide reference for the standardized treatment of venolymphatic insufficiency related diseases in clinical practice.