Clinical characteristics and treatment of myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis

doi:10.3877/cma.j.issn.1674-0785.2024.01.017

Abstract

Abstract:

In 2016, the World Health Organization updated the classification criteria for myelodysplastic syndrome (MDS)/myeloproliferative neoplasm (MPN), which added the classification of myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T). MDS/MPN-RS-T has the dual characteristics of myelodysplasia and myeloproliferation at the same time. Because its incidence rate is extremely low and there are few relevant literature reports, it is very prone to missed diagnosis and misdiagnosis in clinical work, and there is no systematic treatment plan even after diagnosis. This article analyzes and summarizes the relevant reports on the diagnosis and treatment of MDS/MPN-RS-T at home and abroad, with an aim to improve the understanding of this rare disease among clinicians.

Key words: Myelodysplastic syndrome/myeloproliferative neoplasm, Ring sideroblasts, Thrombocythemia, Clinical characteristics, Treatment advances

Wei Jin. Clinical characteristics and treatment of myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis[J]. Chinese Journal of Clinicians(Electronic Edition), 2024, 18(01): 101-104.

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