Progress in noninvasive diagnosis of liver fibrosis in chronic liver disease

doi:10.3877/cma.j.issn.1674-0785.2024.09.011

Abstract

Abstract:

Chronic liver disease can be caused by a variety of factors， such as viral disease，alcohol and non-alcoholic fatty liver disease， autoimmune disorder， drug-induced liver injury， and genetic factors. Liver fibrosis is an important pathological repair reaction to various chronic liver diseases， which is closely related to the development of liver tumors and death. Although liver biopsy is the gold standard for the diagnosis of liver fibrosis， it is invasive and has limited use. The current histopathological fibrosis staging system is not sensitive enough to fibrosis monitoring. Therefore， early and non-invasive diagnosis and accurate staging of liver fibrosis are the key to treating and controlling the progression of fibrosis. This article reviews the progress in research of non-invasive diagnostic methods for liver fibrosis in patients with chronic liver disease.

Key words: Liver fibrosis, Chronic liver disease, Noninvasive diagnosis

Hao Li, Qishuai Chen, Fazhu Fei, Ningwei Zhang, Yuandong Li, Shuochen Wang, Bin Ren. Progress in noninvasive diagnosis of liver fibrosis in chronic liver disease[J]. Chinese Journal of Clinicians(Electronic Edition), 2024, 18(09): 863-867.

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