Long noncoding RNA as biomarkers for tumors

doi:10.3877/cma.j.issn.1674-0785.2019.03.011

Abstract

Abstract:

Long noncoding RNAs (LncRNAs) are a group of noncoding RNA molecules about 200 nt in length, which are involved in the regulation of various cell processes and associated with the development and progression of various cancer types. In recent years, detection of cancer-associated LncRNAs in body fluids of cancer patients has proven as an especially valuable method to effectively diagnose cancer. Compared to conventional tests, LncRNAs have great potential for routine usage in clinical practice due to their relative noninvasiveness. This review focuses on summarizing the perspectives of LncRNA as biomarkers in cancer, based on evaluating their expression profiles in body fluids of cancer patients.

Key words: Long non-coding RNA, Tumor, Biomarkers

Yuanyuan Du, Peng Li, Lingyan Song, Xuxia Guo. Long noncoding RNA as biomarkers for tumors[J]. Chinese Journal of Clinicians(Electronic Edition), 2019, 13(03): 209-213.

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https://zhlcyszz.cma-cmc.com.cn/EN/Y2019/V13/I03/209

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