Application of stereoelectroencephalogram in children with epileptogenic hypothalamic hamartoma

doi:10.3877/cma.j.issn.1674-0785.2021.08.005

Abstract

Abstract:

Objective

To explore the values of stereoelectroencephalogram (SEEG) in the treatment of epilepsy caused by hypothalamic hamartoma in children.

Methods

The clinical data of 17 children with epilepsy secondary to hypothalamic hamartoma admitted to the Department of Neurosurgery, Xuanwu Hospital, Capital Medical University from July 2015 to March 2019 were retrospectively analyzed. All patients underwent SEEG examination and SEEG-guided radiofrequency thermocoagulation. Engel classification was used to evaluate the postoperative efficacy.

Results

A total of 62 electrodes were implanted in 17 patients, and 1 to 6 electrodes were implanted in each patient, with an average of (3.9±1.4) electrodes per patient. The postoperative follow-up time was 24 to 68 months, with an average of (33.9±11.6) months. Epilepsy was completely controlled in nine cases (Engel Ⅰ), partial improvement was achieved in five cases (Engel Ⅲ), and there was no significant improvement in three cases (Engel Ⅳ) after radiofrequency thermocoagulation. No permanent neurological deficit was found.

Conclusion

SEEG-guided radiofrequency thermocoagulation is a safe and effective treatment for epilepsy secondary to hypothalamic hamartoma in children.

Key words: Hypothalamic hamartoma, Stereoelectroencephalogram, Child, Neurosurgical procedures, Radiofrequency thermocoagulation

Tao Feng, Chao Lu, Fei Meng, Yihe Wang, Huaqiang Zhang, Penghu Wei, Yongzhi Shan, Guoguang Zhao. Application of stereoelectroencephalogram in children with epileptogenic hypothalamic hamartoma[J]. Chinese Journal of Clinicians(Electronic Edition), 2021, 15(08): 584-590.

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