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Chinese Journal of Clinicians(Electronic Edition) ›› 2021, Vol. 15 ›› Issue (10): 726-730. doi: 10.3877/cma.j.issn.1674-0785.2021.10.002

• Expert Forum • Previous Articles     Next Articles

Neoadjuvant therapy for human epidermal growth factor receptor 2 positive early breast cancer

Qian Liu1, Hongyu Xiang1, Yinhua Liu1,()   

  1. 1. Breast Disease Center, Peking University First Hospital, Beijing 100034, China
  • Received:2021-07-12 Online:2021-10-15 Published:2022-01-29
  • Contact: Yinhua Liu

Abstract:

Neoadjuvant treatment with Pertuzumab, Trastuzumab and chemotherapy resulted in a statistically significant improvement in the total pathologic complete response rate in human epidermal growth factor receptor 2 (HER2) positive early or locally advanced breast cancer. Among patients with HER2-positive early breast cancer who had residual invasive disease after completion of neoadjuvant therapy, the choice of postoperative adjuvant therapy should be individualized.

Key words: Breast neoplasms, Human epidermal growth factor receptor 2, Neoadjuvant therapy

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