Family function impacts depression in adolescents: the mediatating roles of resilience and negative coping

doi:10.3877/cma.j.issn.1674-0785.2025.11.008

Abstract

Abstract:

Objective

To explore the relationship between family function and the severity of depression, and analyze the chain mediation effect of resilience and negative coping in this relationship.

Methods

A total of 200 adolescents with depression were recruited from Tianjin Anding Hospital, and standard questionnaires were administered for each participant. The family function, resilience, coping style, and depression were assessed by Adaptation Partnership Growth Affection Resolve, Resilience Scale for Chinese Adolescents, Simplified Coping Style Questionnaire, and Beck Depression Inventory-II, respectively. Bootstrap analysis was performed in this study for mediation analysis.

Results

Family function was significantly and positively correlated with resilience (r=0.632, P＜0.001) and significantly and negatively correlated with negative coping and depression (r=-0.561 and -0.570, respectively, P＜0.001). Resilience was significantly and negatively correlated with negative coping and depression (r=-0.666 and -0.641, respectively, P＜0.001). Negative coping was significantly and positively correlated with depression (r=0.972, P＜0.001). Family function was a direct predictor of depression (β=-0.570, P＜0.001) as well as an indirect predictor through the mediating effects of resilience (β=-1.449, 95%CI: -2.161~-0.819) and negative coping (β=-1.273, 95%CI: -4.916~-2.074). Family function was a direct predictor of depression (β=-0.570, P＜0.001) as well as an indirect predictor through the mediating effects of resilience (β=-1.449, 95%CI: -2.161~-0.819), negative coping (β=-1.273, 95%CI: -4.916~-2.074), and the sequential mediation between resilience and negative coping (β=-0.047, 95%CI: -0.209~-0.077).

Conclusion

Family function can directly predict the severity of depression, and can also exert an indirect effect on depression severity through the chain mediation pathway of resilience and negative coping.

Key words: Adolescents, Depression, Family function, Resilience, Negative coping

Yuwei Xia, Peiying Li, Ru Hao, Zeyang Zhao, Fuqiang Mao, Ling Sun. Family function impacts depression in adolescents: the mediatating roles of resilience and negative coping[J]. Chinese Journal of Clinicians(Electronic Edition), 2025, 19(11): 848-853.

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Figures/Tables 5

项目	数值	P值
年龄（岁， $x ¯$ ±s）	15.05±1.70	0.404
性别[例（%）]		0.006
男性	55（37.93）
女性	90（62.07）
独生子女[例（%）]		0.006
是	73（50.34）
否	72（49.66）
居住地[例（%）]		0.169
城市	86（59.31）
城镇	36（24.83）
乡村	23（15.86）
家庭人均月收入[元，例（%）]		0.051
＜3000	5（3.45）
3000~6000	131（90.34）
＞6000	9（6.21）

项目	数值	P值
年龄（岁， $x ¯$ ±s）	15.05±1.70	0.404
性别[例（%）]		0.006
男性	55（37.93）
女性	90（62.07）
独生子女[例（%）]		0.006
是	73（50.34）
否	72（49.66）
居住地[例（%）]		0.169
城市	86（59.31）
城镇	36（24.83）
乡村	23（15.86）
家庭人均月收入[元，例（%）]		0.051
＜3000	5（3.45）
3000~6000	131（90.34）
＞6000	9（6.21）

项目	家庭功能	心理弹性	消极应对	抑郁程度
家庭功能	1
心理弹性	0.632^***	1
消极应对	-0.561^***	-0.666^***	1
抑郁程度	-0.570^***	-0.641^***	0.972^***	1
M	4.55	68.52	12.57	36.02
SD	2.77	18.03	4.65	14.02

回归方程		整体拟合指数			回归系数显著性
结果变量	预测变量	R	R²	F	β	t值
抑郁	家庭功能	0.570	0.325	68.826^***	-0.570	-8.296^***
心理弹性	家庭功能	0.632	0.399	95.131^***	0.632	9.754^***
消极应对	家庭功能	0.982	0.964	102.832^***	-0.946	-46.057^***
消极应对	心理弹性	0.982	0.964	102.832^***	-0.055	-2.693^**
抑郁	家庭功能	0.678	0.459	39.886^***	-0.022	-0.070^*
	心理弹性				-0.453	-5.533^***
	消极应对				0.266	0.815^*

路径	标准化路径效应	效应量占比（%）	95%置信区间
路径	标准化路径效应	效应量占比（%）	下限	上限
1	-1.449	50.28	-2.161	-0.819
2	-1.273	44.17	-4.916	-2.074
3	-0.047	1.63	-0.209	-0.077
间接效应	-2.769	96.08	-6.451	-0.582
直接效应	-0.113	3.92	-3.303	-3.076
总效应	-2.882		-3.569	-2.195

References 34

1	Li X, Wang J. Abnormal neural activities in adults and youths with major depressive disorder during emotional processing: a meta-analysis [J]. Brain Imaging Behav, 2021, 15(2): 1134-1154.
2	田英汉, 刘寰忠. 关注儿童青少年抑郁障碍的初始评估和治疗 [J]. 中华精神科杂志, 2025, 58(11): 807-814.
3	Stallwood E, Monsour A, Rodrigues C, et al. Systematic review: The measurement properties of the children's depression rating scale-revised in adolescents with major depressive disorder [J]. J Am Acad Child Adolesc Psychiatry, 2021, 60(1): 119-133.
4	Hua LL, Lee J, Rahmandar MH, et al. Suicide and suicide risk in adolescents [J]. Pediatrics, 2024, 153(1): e2023064800.
5	胡艳, 汪卫华, 纪菊英, 等. 文拉法辛初始联合坦度螺酮治疗重性抑郁障碍的临床研究 [J/OL]. 中华临床医师杂志(电子版), 2022, 16(8): 725-732.
6	林邹卿, 徐晓燕, 曹磊明, 等. S-氯胺酮治疗重度抑郁症疗效,安全性观察及机制讨论 [J/OL]. 中华临床医师杂志(电子版), 2022, (8): 719-724.
7	谭靓靓, 王坤华, 杨莉, 等. 基于跨理论模型的随访管理对抑郁症患者服药依从性的研究 [J/OL]. 中华临床医师杂志(电子版), 2025, 19(7): 497-503.
8	Sigrist C, Vöckel J, MacMaster FP, et al. Transcranial magnetic stimulation in the treatment of adolescent depression: a systematic review and meta-analysis of aggregated and individual-patient data from uncontrolled studies [J]. Eur Child Adolesc Psychiatry, 2022, 31(10): 1501-1525.
9	尹营营, 袁勇贵. 抑郁症精神运动迟滞的评估方法及生物学机制研究 [J/OL]. 中华临床医师杂志(电子版), 2022, 16(8): 712-718.
10	刘小溪, 岳莹莹, 耿家华, 等. 抗精神病药物浓度监测结果与国内外标准的对比研究 [J/OL]. 中华临床医师杂志(电子版), 2023, 17(10): 1033-1039.
11	Hetrick SE, McKenzie JE, Bailey AP, et al. New generation antidepressants for depression in children and adolescents: a network meta-analysis [J]. Cochrane Database Syst Rev, 2021, 5(5): CD013674.
12	方钟明, 陈静, 蒙衡, 等. 童年创伤和家庭功能对青少年心境障碍患者自伤行为的影响 [J]. 神经损伤与功能重建, 2023, 18(3): 136-139.
13	Zhou X, Bambling M, Bai X, et al. Chinese school adolescents' stress experience and coping strategies: a qualitative study [J]. BMC Psychol, 2023,11(1):91.
14	Esther M, Annabel V, Manon H. Resilience and mental health in children and adolescents: an update of the recent literature and future directions [J]. Curr Opin Psychiatry, 2021, 34(6): 586-592.
15	张钰奇, 娄孟明, 杨紫欣, 等. 大学生心理弹性,社会支持与负性情绪的交叉滞后分析 [J]. 中华行为医学与脑科学杂志, 2025, 34(7): 633-638.
16	Llistosella M, Castellvi P, Limonero JT, et al. Development of the Individual and Environmental Resilience Model among children, adolescents and young adults using the empirical evidence: An integrative systematic review [J]. Health Soc Care Community, 2022, 30(6): e3277-e3299.
17	Guo S, Kaminga AC, Xiong J. Depression and coping styles of college students in China during COVID-19 pandemic: A systemic review and meta-analysis [J]. Front Public Health, 2021, 9: 613321.
18	赵文铎, 丁晴晴, 杨世昌. 应对方式在抑郁症患者童年创伤与抑郁严重程度间的中介作用 [J]. 中华行为医学与脑科学杂志, 2024, 33(9): 838-843.
19	Zhou H, Zhu Z, Feng X, et al. Low mindfulness is related to poor sleep quality from middle adolescents to emerging adults: a process model involving resilience and emotional dysfunction [J]. BMC Psychiatry, 2023, 23(1): 626.
20	王珠珠, 庄嘉元, 赖小兰. 社区护士老年虐待识别水平及其影响因素分析 [J]. 护理研究, 2023, 37(2): 200-206.
21	张作记. 行为医学量表手册 [M]. 北京: 中华医学电子音像出版社, 2005.
22	胡月琴, 甘怡群. 青少年心理韧性量表的编制和效度验证 [J]. 心理学报, 2008, 40(8): 11.
23	解亚宁. 简易应对方式量表信度和效度的初步研究 [J]. 中国临床心理学杂志, 1998, 6(2): 2.
24	Beck AT, Ward CH, Mendelson M, et al. An inventory for measuring depression [J]. Arch Gen Psychiatry, 1961, 4: 561-71.
25	Alfitri R, Kuntoro K, Qomaruddin MB, et al. Exploring the impact of family support and its function on high-risk behaviour among adolescents in Malang City, East Java, Indonesia: A cross sectional study [J]. Afr J Reprod Health, 2024, 28(10s): 74-80.
26	Xie QW, Fan XL, Sun Y, et al. The impact of neighborhood environment on adolescent anxiety and depression: A moderated mediation model involving screen time and family function [J]. J Affect Disord, 2025, 389: 119751.
27	Wang MJ, Chang MY, Gu CF, et al. Psychological adaptation profiles are associated with coping style, social support, and family intimacy in caregivers of children with hematologic malignancies: a cross-sectional study [J]. BMC Nurs, 2025, 24(1): 221.
28	Bian Y, Jin K, Zhang Y. The association between family cohesion and depression: A systematic review and meta-analysis [J]. J Affect Disord, 2024, 355: 220-230.
29	Wang K, Hu Y, He Q, et al. Network analysis links adolescent depression with childhood, peer, and family risk environment factors [J]. J Affect Disord, 2023, 330: 165-172.
30	Song Q, Su W, Li N, et al. Family function and emotional behavior problems in Chinese children and adolescents: A moderated mediation model [J]. J Affect Disord, 2023, 341: 296-303.
31	Gao Y, Wang Y, Wang Z, et al. Family intimacy and adaptability and non-suicidal self-injury: a mediation analysis [J]. BMC Psychiatry, 2024, 24(1): 210.
32	Jung SJ, Jeon YJ, Choi KW, et al. Correlates of psychological resilience and risk: Prospective associations of self-reported and relative resilience with Connor-Davidson resilience scale, heart rate variability, and mental health indices [J]. Brain Behav, 2021, 11(5): e02091.
33	Antosz-Rekucka R, Prochwicz K. Depression and anxiety mediate the relationship between the retrospectively measured symptoms of premenstrual disorders and negative but not positive psychotic-like experiences [J]. Sci Rep, 2023, 13(1): 17711.
34	Kato T. Moderating effect of perceived stress on the relationship between perseverative coping and suicide ideation [J]. Arch Suicide Res, 2025, 3: 1-11.

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