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中华临床医师杂志(电子版) ›› 2023, Vol. 17 ›› Issue (07) : 818 -822. doi: 10.3877/cma.j.issn.1674-0785.2023.07.010

综述

肝脏基础疾病与结直肠癌肝转移之间关系的研究进展
孔凡彪, 杨建荣()   
  1. 530023 南宁,广西壮族自治区人民医院结直肠肛门外科 广西医学科学院微创技术与应用研究所
    530021 南宁,广西壮族自治区人民医院肝胆胰脾外科 广西医学科学院微创技术与应用研究所
  • 收稿日期:2022-08-15 出版日期:2023-07-15
  • 通信作者: 杨建荣
  • 基金资助:
    国家自然科学基金(81660416,82260468); 广西科技重大专项(AA22096018); 广西卫健委自筹经费科研课题(Z20180739,Z20221111); 广西壮族自治区人民医院青年基金(QN2018-22); 广西自然科学基金项目(2023GXNSFAA026341)

Progress in understanding of relationship between underlying liver diseases and liver metastasis of colorectal cancer

Fanbiao Kong, Jianrong Yang()   

  1. Department of Colorectal and Anal Surgery, People's Hospital of Guangxi Zhuang Autonomous Region & Institute of Minimally Invasive Technology and Applications Guangxi Academy of Medical Sciences, Nanning 530023, China
    Department of Hepatobiliary, Pancreatic and Splenic Surgery, People's Hospital of Guangxi Zhuang Autonomous Region & Institute of Minimally Invasive Technology and Applications, Guangxi Academy of Medical Sciences, Nanning 530021, China
  • Received:2022-08-15 Published:2023-07-15
  • Corresponding author: Jianrong Yang
引用本文:

孔凡彪, 杨建荣. 肝脏基础疾病与结直肠癌肝转移之间关系的研究进展[J]. 中华临床医师杂志(电子版), 2023, 17(07): 818-822.

Fanbiao Kong, Jianrong Yang. Progress in understanding of relationship between underlying liver diseases and liver metastasis of colorectal cancer[J]. Chinese Journal of Clinicians(Electronic Edition), 2023, 17(07): 818-822.

结直肠癌肝转移是结直肠癌患者治疗失败的主要原因之一,对于影响肝转移的各种因素也成为结直肠癌的研究热点。肝脏自身基础疾病不仅影响肝脏的功能,而且还与结直肠癌肝转移具有密切的相关性。因此本文结合目前研究热点和进展,主要对肝脏基础疾病,如肝硬化、乙型病毒性肝炎和非酒精性脂肪肝对结直肠癌肝转移的影响及其具体的作用机制等研究进展进行综述,为今后的研究奠定理论基础。

Liver metastasis is one of the main reasons for treatment failure in patients with colorectal cancer, and factors affecting liver metastasis have become a research focus of colorectal cancer. The underlying liver diseases not only affect the function of the liver, but also have a close correlation with liver metastasis of colorectal cancer. This paper reviews the progress in the understanding of the relationship between underlying liver diseases, such as cirrhosis, viral hepatitis B, and non-alcoholic fatty liver, and liver metastasis of colorectal cancer and explores the possible mechanisms involved, laying a theoretical foundation for future research.

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