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中华临床医师杂志(电子版) ›› 2025, Vol. 19 ›› Issue (06) : 467 -470. doi: 10.3877/cma.j.issn.1674-0785.2025.06.011

综述

内镜下胃壁注射A型肉毒毒素减重的研究现状
樊子君1, 王怡婷1, 胡端敏2, 任怡琳1, 盛颖玥1, 刘天浩1, 吴铁龙1, 戴圆圆1, 薛育政1,()   
  1. 1 214000 无锡,江南大学附属医院消化内科
    2 215000 苏州,苏州大学附属第二医院消化内科
  • 收稿日期:2025-06-07 出版日期:2025-06-30
  • 通信作者: 薛育政
  • 基金资助:
    国家自然科学基金委面上项目(32372302); 无锡市太湖人才计划医疗卫生高层次人才项目资助; 无锡市卫健委科研项目(M202027); 无锡市科技局科技医疗与公众健康项目(N20202022)

Current status of research on endoscopic gastric botulinum toxin type A injection for weight loss

Zijun Fan1, Yiting Wang1, Duanmin Hu2, Yilin Ren1, Yingyue Sheng1, Tianhao Liu1, Tielong Wu1, Yuanyuan Dai1, Yuzheng Xue1,()   

  1. 1 Department of Gastroenterology, Affiliated Hospital of Jiangnan University, Wuxi 214000, China
    2 Department of Gastroenterology, The Second Affiliated Hospital of Soochow University, Suzhou 215000, China
  • Received:2025-06-07 Published:2025-06-30
  • Corresponding author: Yuzheng Xue
引用本文:

樊子君, 王怡婷, 胡端敏, 任怡琳, 盛颖玥, 刘天浩, 吴铁龙, 戴圆圆, 薛育政. 内镜下胃壁注射A型肉毒毒素减重的研究现状[J/OL]. 中华临床医师杂志(电子版), 2025, 19(06): 467-470.

Zijun Fan, Yiting Wang, Duanmin Hu, Yilin Ren, Yingyue Sheng, Tianhao Liu, Tielong Wu, Yuanyuan Dai, Yuzheng Xue. Current status of research on endoscopic gastric botulinum toxin type A injection for weight loss[J/OL]. Chinese Journal of Clinicians(Electronic Edition), 2025, 19(06): 467-470.

超重与肥胖的本质是能量摄入超过消耗,由于发病率高、并发症多,影响全球人口的健康。节食、锻炼、药物和手术是常用的治疗手段,但均有局限。目前,内镜下胃壁注射A型肉毒毒素减重的技术正引发关注。本文介绍了该技术的进展,为其合理应用提供依据。

Overweight and obesity are characterized by an imbalance where energy intake exceeds energy expenditure. Due to the high prevalence and numerous complications, they are impacting the global public health. Dieting, exercise, medication, and surgery are common therapeutic approaches, yet all have their limitations. Currently, endoscopic gastric injection of botulinum toxin type A for weight reduction has gained attention. In this paper, we review the advancements in this technique, with an aim to provide a basis for its appropriate application.

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