LARS artificial ligament versus hamstring tendon autograft for anterior cruciate ligament reconstruction: a meta-analysis

doi:10.3877/cma.j.issn.1674-0785.2017.12.005

Abstract

Abstract:

Objective

To systematically evaluate the efficacy of LARS artificial ligament versus autologous hamstring tendon for knee anterior cruciate ligament (ACL) reconstruction by arthroscopy.

Methods

The related articles published from January 1995 to October 2016 were electronically searched. According to the specific inclusion and exclusion criteria, the articles were selected, and then the data were collected and analyzed using RevMan 5.3 software.

Results

A total of 12 controlled clinical trials with Newcastle-Ottawa Scale scores of 4 to 8 were included. A statistical difference was found in the Lysholm score at both 3 and 6 months after surgery between LARS artificial ligament (treatment group) and autologous hamstring tendon (control group), and the treatment group had a significantly higher score. Similar results were also observed for Tegner knee score and IKDC score. However, at 12 months, only the Tegner knee score was higher in the treatment group. At 24 months, there was no significant advantage of the treatment group over the control group with regard to all the three scores mentioned above.

Conclusion

The results of this meta-analysis suggest that LARS artificial ligament has a better clinical outcome than autologous hamstring tendon within 12 months of surgery. This advantage is gradually reduced with the improvement of autologous ligament function, and after 24 months, their clinical outcomes are equivalent. As for longer-term outcomes, further follow-ups and high-quality clinical studies will be needed.

Key words: LARS artificial ligament, Autologous hamstring tendon, Anterior cruciate ligament, Reconstruction

Zhiyong Liang, Tong Xie, Jian Sun, Long Cai, Chuan Xiang. LARS artificial ligament versus hamstring tendon autograft for anterior cruciate ligament reconstruction: a meta-analysis[J]. Chinese Journal of Clinicians(Electronic Edition), 2017, 11(12): 1934-1941.

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References 22

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研究	类型	随访（个月）	实验组			对照组			评级
研究	类型	随访（个月）	男/女（例）	年龄（岁）	受伤时间（个月）	男/女（例）	年龄（岁）	受伤时间（个月）	评级
任磊2015^[8]	回顾性	12	33/12	24	3	15/5	20	3	6星
范文斌2013^[9]	回顾性	24	16/7	30	-	27/4	26	-	5星
唐波2012^[10]	回顾性	12	15/7	32.22	17.18	16/6	33.59	6.2	7星
宁超2012^[11]	回顾性	12	15/3	27.4	5.21	16/4	29.2	4.26	7星
季振涛2011^[12]	回顾性	6	8/5	34.5	-	4/6	33.2	-	5星
王庆峰2011^[13]	前瞻性	24	20/3	28	7.6	20/9	27	9.7	5星
Liu 2009^[14]	回顾性	49	21/7	36	8	24/8	32	9	8星
陆晴友2009^[7]	回顾性	12	15	35	3.5	20	35	3.5	4星
张兵2009^[15]	回顾性	9	12/6	29.94	5.17	15/7	30.14	6.59	5星
范钦波2008^[16]	前瞻性	12	12/3	29.8	6	22/5	29.8	6	7星
黄长明2007^[17]	回顾性	9	11	35	-	9	35	-	5星
陈世益2007^[18]	前瞻性	15	13/10	28.2	-	11/8	27.1	-	8星

研究	类型	随访（个月）	实验组			对照组			评级
研究	类型	随访（个月）	男/女（例）	年龄（岁）	受伤时间（个月）	男/女（例）	年龄（岁）	受伤时间（个月）	评级
任磊2015^[8]	回顾性	12	33/12	24	3	15/5	20	3	6星
范文斌2013^[9]	回顾性	24	16/7	30	-	27/4	26	-	5星
唐波2012^[10]	回顾性	12	15/7	32.22	17.18	16/6	33.59	6.2	7星
宁超2012^[11]	回顾性	12	15/3	27.4	5.21	16/4	29.2	4.26	7星
季振涛2011^[12]	回顾性	6	8/5	34.5	-	4/6	33.2	-	5星
王庆峰2011^[13]	前瞻性	24	20/3	28	7.6	20/9	27	9.7	5星
Liu 2009^[14]	回顾性	49	21/7	36	8	24/8	32	9	8星
陆晴友2009^[7]	回顾性	12	15	35	3.5	20	35	3.5	4星
张兵2009^[15]	回顾性	9	12/6	29.94	5.17	15/7	30.14	6.59	5星
范钦波2008^[16]	前瞻性	12	12/3	29.8	6	22/5	29.8	6	7星
黄长明2007^[17]	回顾性	9	11	35	-	9	35	-	5星
陈世益2007^[18]	前瞻性	15	13/10	28.2	-	11/8	27.1	-	8星

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