Association between peripheral blood levels of 25(OH)D and hypersensitive C-reactive protein in patients with inflammatory and non-inflammatory diseases

doi:10.3877/cma.j.issn.1674-0785.2019.06.010

Abstract

Abstract:

Objective

To investigate the correlation between peripheral blood levels of 25-hydroxyvitamin D [25(OH)D] and hypersensitive C-reactive protein (hs-CRP) in patients with inflammatory and non-inflammatory diseases.

Methods

A total of 281 patients (130 patients with inflammatory disease and 151 cases with non-inflammatory disease) were involved in this study between September 2017 and November 2017. The levels of 25(OH)D and hs-CRP in peripheral blood were detected by electrochemiluminescence and turbidimetry, respectively.

Results

The levels of 25(OH)D in the inflammatory disease group were significantly negatively correlated with those of hs-CRP (r=-0.780, P<0.001). In the non-inflammatory disease group, the 25(OH)D levels and hs-CRP concentrations had a weaker negative association (r=-0.636, P<0.001).

Conclusion

Peripheral blood levels of 25(OH)D are negatively associated with hs-CRP not only in patients with inflammatory disease but also in non-inflammatory populations. The correlation in the inflammatory group is significantly higher than that in the non-inflammatory group.

Key words: High-sensitivity, 25-hydroxy vitamin D, Inflammatory disease, Inflammatory

Liying Zhou, Li Jiang. Association between peripheral blood levels of 25(OH)D and hypersensitive C-reactive protein in patients with inflammatory and non-inflammatory diseases[J]. Chinese Journal of Clinicians(Electronic Edition), 2019, 13(06): 454-456.

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URL: https://zhlcyszz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1674-0785.2019.06.010

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Figures/Tables 2

References 10

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