To identify the risk factors for the occurrence of multiple organ dysfunction syndrome (MODS) in patients with bee sting injury.

A retrospective analysis was conducted on patients with bee sting injury who were hospitalized at the First People' s Hospital of Yulin City, Guangxi from January 2015 to December 2020. The patients were divided into either an MODS group (27 cases) or a non-MODS group (84 cases) based on the presence or absence of MODS. The differences in clinical data between the two groups were compared. Logistic regression analysis was used to identify the risk factors for MODS, and the optimal cutoff points for relevant risk factors were analyzed using ROC curves.

Among the 111 cases of bee sting injury included, the incidence of MODS was 24.3%. In the MODS group, the age, duration of injury, length of hospital stay, rate of endotracheal intubation after hospitalization, occurrence rate of acute kidney injury, hematuria, and proteinuria, direct bilirubin, lipase, rate of elevated lipase, blood creatinine, high-sensitivity cardiac troponin T, plasma prothrombin time, and activated partial thromboplastin time were higher than those in the non-MODS group, while serum albumin and coagulation factor activity were lower (P<0.05 for all). Logistic regression analysis indicated that the independent risk factors for MODS in patients with bee sting injury were the presence of proteinuria, decrease in serum albumin, and elevation of lipase. The risk of MODS in patients with proteinuria was 21.125 times that of patients without, and the risk of MODS in patients with elevated lipase was 7.033 times that of patients with normal lipase. The logistic regression model combined with ROC curve analysis suggested that the risk of MODS in patients with bee sting injury with a serum albumin level < 37.05 g/L was 25.9 times higher than that of patients with a serum albumin level ≥ 37.05 g/L (P<0.001).

Patients with bee sting injury who present with proteinuria, elevated lipase, and serum albumin level <37.05 g/L have a significantly increased risk of developing MODS and require early and proactive prevention and treatment.