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Chinese Journal of Clinicians(Electronic Edition) ›› 2022, Vol. 16 ›› Issue (07): 685-690. doi: 10.3877/cma.j.issn.1674-0785.2022.07.016

• Clinical Research • Previous Articles     Next Articles

Relationship between resting heart rate and arterial stiffness in apparently normal She minority people in Fujian Province

Wei Huang1, Xiuqin Wu2, Huan Liu1, Yongqiang Hong2, Hongyu Wang1,()   

  1. 1. Department of Vascular Medicine, Peking University Shougang Hospital, Beijing 100144, China
    2. Ultrasound Department of Mindong Hospital Affiliated to Fujian Medical University, Fujian 355000, China
  • Received:2021-11-09 Online:2022-07-15 Published:2022-10-08
  • Contact: Hongyu Wang

Abstract:

Objective

To evaluate the relationship between resting heart rate (RHR) and arterial stiffness in apparently normal She minority people from Fujian Province, China.

Methods

A total of 511 She minority participants from six natural villages were enrolled into this study using cluster sampling method in 2009. Eventually, 325 subjects with full data were analyzed. All subjects were detected for carotid femoral pulse wave velocity (CF-PWV), carotid radial pulse wave velocity (CR-PWV), cardio ankle vascular index (CAVI), ankle brachial index (ABI), and carotid intima media thickness (CIMT) by Doppler ultrasound, and blood tests were performed for measuring fasting plasma glucose (FPG), blood lipids, blood uric acid (UA), and high sensitive C reactive protein (hs-CRP). RHR was the mean of three values measured using VS-1000 vascular detection equipment and ultrasound equipment.

Results

Systolic blood pressure (SBP), diastolic blood pressure (DBP), total cholesterol/high density lipoprotein cholesterol ratio (TC/HDL-C), HDL-C, CF-PWV, and CR-PWV were significantly different among participants classified into different quartiles of RHR (RHR1: ≤61 beats/min; RHR2: 62~69 beats/min; RHR3: 70~77 beats/min; RHR4: ≥78 beats/min) (P<0.05); SBP, DBP, TC/HDL-C, CF-PWV, and CR-PWV in the RHR4 group were significantly higher than those in the RHR1 group (P<0.05), but HDL-C in the RHR4 group was significantly lower than that of the RHR1 group (P<0.05). However, there were no statistical difference in CAVI, ABI, or CIMT among different RHR groups (P>0.05). Logistic regression analysis indicated in the model without adjustment, RHR4 was associated with higher CF-PWV (CF-PWV>9 m/s; odds ratio [OR]=3.074, 95% confidence interval [CI]: 1.555~6.075, P<0.05) compared with RHR1. After adjustment for age and gender, the OR of RHR4 was 4.542 (95%CI: 2.078~9.928, P<0.05). And after further adjustment for SBP, DBP, plasma lipids, FPG, and hs-CRP, the OR of RHR4 was 5.336 (95%CI: 1.512~18.831, P<0.05).

Conclusion

In apparently normal She minority people in Fujian Province, China, high RHR is followed by high levels of blood pressure, plasma lipids, and arterial stiffness. Furthermore, higher rest heart rate is independently associated with arterial stiffness.

Key words: She minority, Resting heart rate, Arterial stiffness

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