To analyze the clinical data of patients with internal jugular vein thrombosis confirmed by ultrasound, and identify its potential high-risk factors and related hazards.

The clinical data of 139 patients diagnosed with internal jugular vein thrombosis by ultrasound examination at Hua Mei Hospital from January 2017 to May 2020 were analyzed. Among them, 91 were male and 48 were female, with a mean age of (61.55±10.32) years. In the meantime, 150 people with normal results of internal jugular vein ultrasonography were randomly selected as a control group, including 102 males and 48 females, with a mean age of (60.71±12.32) years. Gender, age, coagulation function, cardiac function, local stenosis of the internal jugular vein, history of puncture and catheterization of the internal jugular vein, history of malignant tumor, history of transient total amnesia, history of transient monocular blindness, history of cognitive impairment, lateral differentiation of intrajugular venous thrombosis, and presence or absence of thrombosis in the intracranial venous sinus were compared between the two groups, and multivariate logistic regression analysis was performed to determine the risk factors for intrajugular venous thrombosis.

Univariate analysis showed that there were statistically significant differences between the two groups in coagulation function, local stenosis of the internal jugular vein, history of puncture catheterization of the internal jugular vein, history of malignancy, history of transient total amnesia, history of transient blindness of one eye, history of cognitive impairment, and intrajugular vein thrombosis (P＜0.05 for all). Multivariate logistic regression analysis showed that international normalized ratio (INR) [odds ratio (OR)=4.171, 95% confidence interval (CI): 1.072-16.234], D dimer (OR=4.421, 95%CI: 1.957-9.986), local stenosis of the internal jugular vein (OR=75.250, 95%CI: 30.106-188.090), history of internal jugular vein puncture catheterization (OR=13.188, 95%CI: 2.006-86.704), and history of malignant tumor (OR=75.250, 95%CI: 30.106, 188.090) were risk factors for internal jugular vein thrombosis.

Abnormal INR, abnormal D-dimer, local stenosis of the internal jugular vein, history of internal jugular vein puncture, and history of malignant tumor are high-risk factors for internal jugular vein thrombosis. Patients with internal jugular vein thrombosis are more prone to transient global amnesia, transient monocular blindness, and cognitive impairment.