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Chinese Journal of Clinicians(Electronic Edition) ›› 2025, Vol. 19 ›› Issue (06): 467-470. doi: 10.3877/cma.j.issn.1674-0785.2025.06.011

• Review • Previous Articles    

Current status of research on endoscopic gastric botulinum toxin type A injection for weight loss

Zijun Fan1, Yiting Wang1, Duanmin Hu2, Yilin Ren1, Yingyue Sheng1, Tianhao Liu1, Tielong Wu1, Yuanyuan Dai1, Yuzheng Xue1,()   

  1. 1 Department of Gastroenterology, Affiliated Hospital of Jiangnan University, Wuxi 214000, China
    2 Department of Gastroenterology, The Second Affiliated Hospital of Soochow University, Suzhou 215000, China
  • Received:2025-06-07 Online:2025-06-30 Published:2025-11-06
  • Contact: Yuzheng Xue

Abstract:

Overweight and obesity are characterized by an imbalance where energy intake exceeds energy expenditure. Due to the high prevalence and numerous complications, they are impacting the global public health. Dieting, exercise, medication, and surgery are common therapeutic approaches, yet all have their limitations. Currently, endoscopic gastric injection of botulinum toxin type A for weight reduction has gained attention. In this paper, we review the advancements in this technique, with an aim to provide a basis for its appropriate application.

Key words: Botulinum toxin type A, Obesity, Therapy

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