Risk factors and characteristics of coronary lesions in patients with acute myocardial infarction of different gender andage

doi:10.3877/cma.j.issn.1674-0785.2019.02.002

Abstract

Abstract:

Objective

To analyze the regional characteristics of risk factors and coronary artery lesions in patients with acute myocardial infarction (AMI) of different genders and age groups in Qingdao, where there is a high incidence of coronary heart disease.

Methods

From January to October 2017, 1050 AMI patients admitted to the Affiliated Hospital of Qingdao University were divided into male (n=683) and female (n=367) groups,<50 years old (n=124 cases), 50-59 years old (n=199 cases), 60-69 years old (n=330 cases), and≥70 years old (n=397 cases) group according to gender and age. The risk factors and characteristics as well as coronary lesions were analyzed.

Results

The average age of onset of male AMI patients was significantly lower than that of females [(62.01±12.35) years old vs (71.43±9.75) years old, P<0.01). With the increase of age, the proportion of smoking patients and the body mass index (BMI) of patients showed a downward trend, while the proportion of female patients gradually increased. The proportion of patients with hypertension increased first and then decreased with age, with the highest proportion observed in the 60-69 age group (62.4%). The proportion of male patients with hypertension was higher than that of females (54.9% vs 46.1%, P<0.05). The proportion of patients with diabetes increased with age, and after the age of 60, the proportion of women with diabetes in all ages is higher than that of men (40.0% vs 27.3%, 42.6% vs 26.4%, P<0.05 of all), especially in patients with ST-segment elevation myocardial infarction; the proportion of women with diabetes was up to 55.6% in the 50-59 age group. With the increase of age, triacylglycerol (TG) levels gradually decreased, and high-density lipoprotein (HDL-C) levels gradually increased. Coronary angiography results showed that the number of vascular lesions in patients with AMI increased with age. In patients aged<50 years, the single vessel lesion rate was as high as 50.9%; patients aged<50 years were most commonly diagnosed with LAD lesions; in patients aged>70 years, LAD and right coronary artery (RCA) lesions were more common.

Conclusion

Different prevention and treatment measures can be taben for AMI patients of different gender and age.

Key words: Acute myocardial infarction, Gender, Age, Risk factors, Coronary artery disease

Ruicong Sun, Xianming Chu, Haichu Yu, Zhexun Lian, Qingke Xu, Bing Li. Risk factors and characteristics of coronary lesions in patients with acute myocardial infarction of different gender andage[J]. Chinese Journal of Clinicians(Electronic Edition), 2019, 13(02): 87-94.

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Figures/Tables 8

References 28

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组别	例数	年龄（岁）	BMI（kg/m²）	STEMI［例（%）］	吸烟史［例（%）］	高血压病史［例（%）］	糖尿病史［例（%）］	TG（mmol/L）	TC（mmol/L）	HDL-C（mmol/L）	LDL-C（mmol/L）
男性	683	62.01±12.35	25.55±3.45	315（46.1）	449（65.7）	375（54.9）	163（23.9）	1.67±1.26	4.44±1.15	1.11±0.29	2.63±0.89
女性	367	71.43±9.75	25.32±6.51	135（35.4）	22（6.0）	169（46.1）	148（40.3）	1.74±1.43	4.82±1.28	1.24±0.31	2.8±0.94
统计值	?	t=-13.558	t=0.632	χ²=11.188	χ²=344.491	χ²=7.499	χ²=31.033	t=-0.73	t=-4.674	t=-6.42	t=-2.815
P值	?	<0.01	0.534	<0.01	<0.01	<0.01	<0.01	0.465	<0.01	<0.01	<0.01

组别	例数	年龄（岁）	BMI（kg/m²）	STEMI［例（%）］	吸烟史［例（%）］	高血压病史［例（%）］	糖尿病史［例（%）］	TG（mmol/L）	TC（mmol/L）	HDL-C（mmol/L）	LDL-C（mmol/L）
男性	683	62.01±12.35	25.55±3.45	315（46.1）	449（65.7）	375（54.9）	163（23.9）	1.67±1.26	4.44±1.15	1.11±0.29	2.63±0.89
女性	367	71.43±9.75	25.32±6.51	135（35.4）	22（6.0）	169（46.1）	148（40.3）	1.74±1.43	4.82±1.28	1.24±0.31	2.8±0.94
统计值	?	t=-13.558	t=0.632	χ²=11.188	χ²=344.491	χ²=7.499	χ²=31.033	t=-0.73	t=-4.674	t=-6.42	t=-2.815
P值	?	<0.01	0.534	<0.01	<0.01	<0.01	<0.01	0.465	<0.01	<0.01	<0.01

组别	例数	年龄（岁）	女性［例（%）］	BMI（kg/m²）	STEMI［例（%）］	吸烟史［例（%）］	高血压病史［例（%）］	糖尿病史［例（%）］	TG（mmol/L）	TC（mmol/L）	HDL-C（mmol/L）	LDL-C（mmol/L）
<50岁	124	43.81±4.72	7（5.6）	26.92±3.84	66（53.2）	82（66.1）	52（41.9）	19（15.3）	2.16±1.68	4.54±1.35	1.07±0.26	2.69±1.06
50~59岁	199	54.74±2.66	31（15.6）	26.12±2.94	83（41.7）	110（55.3）	111（55.8）	48（24.1）	1.84±1.38	4.63±1.18	1.13±0.27	2.69±1.06
60~69岁	330	64.72±2.85	125（37.9）	25.12±3.31	129（39.1）	164（49.7）	206（62.4）	106（32.1）	1.66±1.14	4.52±1.10	1.18±0.33	2.67±0.84
≥70岁	397	77.79±5.46	204（51.4）	24.97±6.36	167（42.1）	115（29.0）	175（44.1）	138（34.8）	1.51±1.26	4.60±1.26	1.18±0.30	2.68±0.92
统计值	?	F=2650.212	χ²=128.01	F=7.341	χ²=2.504	χ²=26.846	χ²=10.427	χ²=7.14	F=8.729	F=0.416	F=5.183	F=0.247
P值	?	<0.01	<0.01	<0.01	0.058	<0.01	<0.01	<0.01	<0.01	0.741	<0.01	0.864

组别	例数	年龄（岁）	女性［例（%）］	BMI（kg/m²）	STEMI［例（%）］	吸烟史［例（%）］	高血压病史［例（%）］	糖尿病史［例（%）］	TG（mmol/L）	TC（mmol/L）	HDL-C（mmol/L）	LDL-C（mmol/L）
<50岁	124	43.81±4.72	7（5.6）	26.92±3.84	66（53.2）	82（66.1）	52（41.9）	19（15.3）	2.16±1.68	4.54±1.35	1.07±0.26	2.69±1.06
50~59岁	199	54.74±2.66	31（15.6）	26.12±2.94	83（41.7）	110（55.3）	111（55.8）	48（24.1）	1.84±1.38	4.63±1.18	1.13±0.27	2.69±1.06
60~69岁	330	64.72±2.85	125（37.9）	25.12±3.31	129（39.1）	164（49.7）	206（62.4）	106（32.1）	1.66±1.14	4.52±1.10	1.18±0.33	2.67±0.84
≥70岁	397	77.79±5.46	204（51.4）	24.97±6.36	167（42.1）	115（29.0）	175（44.1）	138（34.8）	1.51±1.26	4.60±1.26	1.18±0.30	2.68±0.92
统计值	?	F=2650.212	χ²=128.01	F=7.341	χ²=2.504	χ²=26.846	χ²=10.427	χ²=7.14	F=8.729	F=0.416	F=5.183	F=0.247
P值	?	<0.01	<0.01	<0.01	0.058	<0.01	<0.01	<0.01	<0.01	0.741	<0.01	0.864

组别	例数	年龄（岁）	BMI（kg/m²）	STEMI［例（%）］	吸烟史［例（%）］	高血压病史［例（%）］	糖尿病史［例（%）］	TG（mmol/L）	TC（mmol/L）	HDL-C（mmol/L）	LDL-C（mmol/L）
<50岁	117	43.64±4.80	27.02±3.90	61（52.1）	82（70.1）	48（41.0）	17（14.5）	2.19±1.71	4.59±1.37	1.07±0.27	2.72±1.07
50~59岁	168	54.51±2.61	26.13±2.81	74（44.1）	105（62.5）	93（55.4）	39（23.2）	1.79±1.15	4.54±1.09	1.11±0.27	2.71±0.83
60~69岁	205	64.63±2.85	25.20±3.15	89（43.4）	157（76.6）	118（57.6）	56（27.3）	1.67±1.26	4.41±1.08	1.15±0.34	2.61±0.84
≥70岁	193	76.87±5.43	24.51±3.60	91（47.2）	105（54.4）	116（60.1）	51（26.4）	1.27±0.82	4.31±1.12	1.11±0.26	2.54±0.86
统计值	?	F=1892.638	F=16.136	χ²=2.681	χ²=23.481	χ²=11.808	χ²=7.691	F=14.420	F=2.018	F=1.886	F=1.555
P值	?	<0.05	<0.05	0.443	<0.05	<0.05	0.053	<0.01	0.11	0.131	0.199

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