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Chinese Journal of Clinicians(Electronic Edition) ›› 2021, Vol. 15 ›› Issue (03): 218-223. doi: 10.3877/cma.j.issn.1674-0785.2021.03.013

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Progress in research of HPV vaccine and influencing factors in process of promotion and vaccination

Xumei Yang1, Rongrong Jin2, Huiling Zhou2, Xiaoqin Jiang2, Hong Yu2()   

  1. 1. Department of Clinical Pathology, Graduate School of Dalian Medical University, Dalian 116044, China; Department of Pathology, Taizhou People's Hospital, Taizhou 225300, China
    2. Department of Pathology, Taizhou People's Hospital, Taizhou 225300, China
  • Received:2020-09-15 Online:2021-03-15 Published:2021-08-06
  • Contact: Hong Yu

Abstract:

HPV infection is the main cause of cervical cancer and other HPV-related diseases. There has been a remarkable decline in the morbidity and mortality of cervical cancer and its related diseases after the popularization and application of HPV vaccines in the past ten years. HPV vaccine has only been recently licensed in China, and there are still many influencing factors in the process of promotion and vaccination, e.g., adverse events, lower awareness rate, high cost, supply shortage, worry about safety and effectiveness, and lack of HPV-related knowledge. This paper reviews the progress in the research of HPV and HPV vaccine and the influencing factors in the popularization and application of HPV vaccine in order to provide information to help increase the coverage rate of HPV vaccine and develop a new locally produced HPV vaccine that is cheap, safe, and effective.

Key words: Human papillomavirus, Vaccine, Adverse event, Knowledge

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