High-risk HPV infection among women in western Beijing: characteristics and genotype distribution

doi:10.3877/cma.j.issn.1674-0785.2022.09.015

Abstract

Abstract:

Objective

To explore the characteristics of high-risk human papilloma virus (HPV) infection in the female population in western Beijing and analyze the distribution of HPV genotypes.

Methods

A total of 14946 female patients from western Beijing who were admitted to Peking University Shougang Hospital from January 2018 to June 2021 were selected as subjects. Their cervical exfoliated cells were subjected to real-time Taqman polymerase chain reaction (PCR) for high-risk HPV typing. HPV infection rate and genotype distribution were statistically analyzed.

Results

Among the 14946 samples detected, a total of 2449 cases were found to be positive, with an infection rate of 16.39%. The single type HPV infection rate was 12.86%, and the multiple type HPV infection rate was 3.53%. HPV52 (17.06%) was the most common genotype, followed by HPV16 (14.95%) and HPV58 (12.80%). A high rate of HPV infection of 17.99% and 18.06% was found in women aged 20~29 years and those aged 60~69 years, respectively. The overall infection rate curve showed a "basin" trend distribution.

Conclusion

HPV infection rate among women in western Beijing is relatively high. Measures should be taken to reduce the risk and disease burden of HPV infection in women by timely vaccination, regular follow-up, and raising awareness of cervical cancer screening.

Key words: Human papillomavirus, Infection status, Genotyping

Linlin Zhu, Fan Zhao, Linlin Yan, Fengzhi Zheng, Jing Wang, Shoukui Hu. High-risk HPV infection among women in western Beijing: characteristics and genotype distribution[J]. Chinese Journal of Clinicians(Electronic Edition), 2022, 16(09): 897-901.

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Figures/Tables 4

References 14

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感染情况	n	占比（%）
单一感染	1922	78.48
二重感染	415	16.95
三重感染	83	3.39
四重感染	23	0.94
五重感染	5	0.20
六重感染	1	0.04
合计	2449	100.00

感染情况	n	占比（%）
单一感染	1922	78.48
二重感染	415	16.95
三重感染	83	3.39
四重感染	23	0.94
五重感染	5	0.20
六重感染	1	0.04
合计	2449	100.00

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