Current advances and developments in diagnosis and treatment of small cell osteosarcoma

doi:10.3877/cma.j.issn.1674-0785.2024.08.013

Abstract

Abstract:

Small cell osteosarcoma is a rare subtype of osteosarcoma with a poor prognosis.It is difficult to differentiate small cell osteosarcoma histopathologically from other malignant bone small cell tumors， especially Ewing’s sarcoma， due to their very similar immunohistochemical features.A diagnosis cannot be made by local puncture or biopsy when no tumor-affected bone is obtained， which affects the treatment plan.Therefore， it is of great significance to make a definite diagnosis of small cell osteosarcoma before surgery.This article briefly reviews the clinical， imaging， pathological， therapeutic， and prognostic features of small cell osteosarcoma.

Key words: Small cell osteosarcoma, Immunohistochemistry, Diagnosis

Ruiyi Tan. Current advances and developments in diagnosis and treatment of small cell osteosarcoma[J]. Chinese Journal of Clinicians(Electronic Edition), 2024, 18(08): 783-786.

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