To analyze and summarize the prenatal echocardiographic features of fetal congenitally corrected transposition of the great arteries (cc-TGA).

The echocardiographic images of five cases of fetal cc-TGA diagnosed and confirmed by the postnatal pathology or postpartum pediatric echocardiography at the Harbin Red Cross Center Hospital from January 2011 to December 2017 were retrospectively analyzed to explore the prenatal echocardiography characteristics, diagnosis, and differential diagnosis of cc-TGA.

Of the five cases of cc-TGA , four were confirmed by anatomical pathology after induced labor, and one was confirmed by postpartum echocardiography (the child was in good condition 90 days after delivery). Two of the five cc-TGA cases underwent chromosome examination, and the karyotype was normal. With regard to prenatal echocardiography in the five cases, the four-chamber heart view combined with upper abdominal cross-section, the left and right ventricular outflow view, the view of the aortic arch and ductal arch, the three-vessel view (3VV), and the three-vessel trachea view (3VT) showed characteristic manifestations. Prenatal echocardiography revealed multiple intracardiac and extracardiac malformations; in four cases of SLL type, ventricular septal defect (VSD) was observed in three cases, pulmonary artery atresia in two, pulmonary artery stenosis in one, persistent left superior vena in two, atrioventricular regurgitation in two, and endocardial cushion defect (ECD) in one; one case of SLL type was complicated with multiple extracardiac malformations, including lateral ventricles hydrocephalus, spina bifida, and strephenopodia in both feet; one case of IDD was associated with multiple intracardiac malformations, including ventricular septal defect, mild pulmonary artery stenosis, right aortic arch, and extracardiac malformations with situs inversus of abdominal organs.

Understanding the features of echocardiography in various views of cc-TGA can help effectively detect and diagnose this disease. The prognosis of fetal cc-TGA is very different, depending on the severity of relevant defects.