Abstract:

Objective

To summarize our clinical experience with Pseudomonas aeruginosa injection in the treatment of refractory high-output chyle leakage in the neck.

Methods

In this study, we retrospectively analyzed the clinical data of two patients with refractory high-output chyle leakage after cervical lymph node dissection for thyroid cancer admitted to Cancer Hospital & Shenzheng Hospital,Chinese Academy of Medical Sciences, of which 1 was female and 1 was male.Both patients underwent primary surgery.Both patients were considered to have chyle leakage caused by the rupture of the thoracic duct at the left neck, and the maximum daily drainage volume exceeded 1000 ml.

Results

The patients had poor response to conservative therapy, and both of them received retrograde injection of Pseudomonas aeruginosa injection through the left cervical drain, and were finally discharged from the hospital without serious complications and sequelae.

Conclusion

Pseudomonas aeruginosa injection in the operative area is effective and safe in the treatment of refractory high-output chyle leakage in the neck, and it can significantly shorten the duration of chyle leakage.

Key words: Pseudomonas aeruginosa injection, Chyle leakage, Cervical lymph node dissection, Thyroid cancer